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J-GLOBAL ID：200902221893167828   Reference number：05A0590474

Evolution in the hypervariable region of the hepatitis C virus in two infants infected by mother-to-infant transmission

母子伝染の2感染児におけるC型肝炎ウイルス超可変領域の進化

Author (8)： ISHII Tsutomu (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  OHTO Hitoshi (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  TAKEUCHI Chikako (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  ARIGA Hiromichi (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  HIRAI Shigeru (National Fukushima Hospital, Fukushima, JPN) ,  UJIIE Niro (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  SUZUKI Hitoshi (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  OKAMOTO Hiroaki (Jichi Medical School, Tochigi, JPN)
Material： Pediatrics International  (Pediatr Int)
Volume： 47  Issue： 3  Page： 278-285  Publication year： Jun. 2005 
JST Material Number： W1358A  ISSN： 1328-8067  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： GPT ,...

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JST classification (4)： Diseases specific to children  (GC08020M) ,  Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Microorganism biochemistry  (EG03020N) ,  Digestive system diseases  (GH03000W)

Reference (20)：

• OHTO, H. Transmission of hepatitis C virus from mothers to infants. N. Engl. J. Med. 1994, 330, 744-750
• SPENCER, JD. Transmission of hepatitis C virus to infants of human immunodeficiency virus-negative intravenous drug-using mothers : Rate of infection and assessment of risk factors for transmission. J. Viral Hepat. 1997, 4, 395-409
• SASAKI, N. Loss of circulating hepatitis C virus in children who developed a persistent carrier state after mother-to-baby transmission. Pediatr. Res. 1997, 42, 263-267
• KATO, N. Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J. Virol. 1993, 67, 3923-3930
• OKADA, S. The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients. Hepatology. 1992, 16, 619-624

Terms in the title (5)： 伝染 ,  感染 ,  C型肝炎ウイルス ,  超可変領域 ,  進化