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J-GLOBAL ID：200902222518028736   Reference number：07A0806674

Deletion patterns of derivative chromosome 9 in three patients with chronic myeloid leukemia shown by dual-fusion FISH probe system

派生9番染色体上の転座融合点領域欠失を伴う慢性骨髄性白血病3例のFISH法解析

Author (7)： HOSAKA RIE (埼玉県がんセ 検査技術部) ,  SATAKE KAZUMI (埼玉県がんセ 検査技術部) ,  KURIHARA MASATO (埼玉県がんセ 検査技術部) ,  KOYAMA MASAHIRO (埼玉県がんセ 検査技術部) ,  HOSHI CHIHARU (埼玉県がんセ 検査技術部) ,  SAKURAI HIROSHI (埼玉県がんセ 検査技術部) ,  HASEGAWA SHOICHI (埼玉県がんセ 検査技術部)
Material： 医学検査  (Japanese Journal of Medical Technology)
Volume： 56  Issue： 8  Page： 1125-1131  Publication year： Aug. 25, 2007 
JST Material Number： S0681B  ISSN： 0915-8669  CODEN： IGKEES  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *autosome ,...
Semi thesaurus term： *Chromosomes, Human, Pair 9 ,...

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JST classification (3)： Blood cell tumors(=neoplasms)  (GK04000M) ,  Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Genetic variation  (EC01030Y)

Reference (15)：

• KOLOMIETZ, E. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may load to altered prognosis. Blood. 2001, 97, 3581-3588
• HERENS, C. Deletion of 5'-ABL region : a recurrent anomaly detected by fluorescence in situ hybridization in about 10% of Philadelphia-positive chronic myeloid leukaemia patients. Br J Hematol. 2000, 110, 214-216
• FOURNIER, M. Deletions of the 3'BCR and 5'ABL regions in patients with Philadelphia-positive chronic myeloid leukemia : a one-step process occurring in about 10% of the cases without any evidence of genetic instability in the target cells. Cancer Genet Cytogenet. 2005, 160, 184-187
• SINCLAIR, PB. Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia. Blood. 2000, 95, 738-744
• STORLAZZI, CT. Breakpoint Characterization of der (9) Deletions in Chronic Myeloid Leukemia Patients. Gene Chromosome Cancer. 2002, 35, 271-276

Terms in the title (7)： 9番染色体 ,  転座 ,  融合 ,  欠失 ,  慢性骨髄性白血病 ,  FISH法 ,  解析