Art

J-GLOBAL ID：200902225912897102   Reference number：09A0796118

An alternative menaquinone biosynthetic pathway operating in microorganisms: an attractive target for drug discovery to pathogenic Helicobacter and Chlamydia strains

微生物で働くもう一つのメナキノン生合成経路:病原性HilicabacterおよびChlamydia属に対する薬物発見のための魅力的な標的

Author (1)： DAIRI Tohru (Toyama Prefectural Univ., Toyama, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 62  Issue： 7  Page： 347-352  Publication year： Jul. 2009 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： biosynthesis ,...
Semi thesaurus term： フタロシン経路 ,...

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JST classification (1)： Synthesis of antibiotics  (GX04000Z)

Reference (28)：

• BENTLEY, R. Biosynthesis of vitamin K (menaquinone) in bacteria. Microbiol. Rev. 1982, 46, 241-280
• MEGANATHAN, R. Biosynthesis of menaquinone (vitamin K2) and ubiquinone (coenzyme Q) : a perspective on enzymatic mechanisms. Vitam. Horm. 2001, 61, 173-218
• DAHLBACK, B. Regulation of blood coagulation by the protein c anticoagulant pathway : novel insights into structure-function relationships and molecular recognition. Artern. Thromb. Vasc. Biol. 2005, 25, 1311-1320
• ADAMS, J. Vitamin K in the treatment and prevention of osteoporosis and arterial calcification. Am. J. Health Syst. Pharm. 2005, 62, 1574-1581
• LAMSON, D. W. The anticancer effects of vitamin K. Altern. Med. Rev. 2003, 8, 303-318

Terms in the title (9)： 微生物 ,  メナキノン ,  生合成経路 ,  病原性 ,  Chlamydia属 ,  薬物 ,  発見 ,  魅力 ,  標的