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J-GLOBAL ID：200902226589926757   Reference number：08A0631472

Blocking Histamine H₁ Improves Learning and Mnemonic Dysfunction in Mice With Social Isolation Plus Repeated Methamphetamine Injection

ヒスタミンH1阻害は社会的隔離とメタンフェタミン反復投与を受けたマウスの学習と記憶障害を改善する

Author (14)： JIA Feiyong (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  JIA Feiyong (Dep. of Pediatrics, The First Hospital of Jilin Univ., CHN) ,  JIA Feiyong (Dep. of Pediatrics, Tohoku Univ. School of Medicine, JPN) ,  MOBARAKEH Jalal Izadi (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  MOBARAKEH Jalal Izadi (Dep. of Pharmacology and Physiology, Pasteur Inst. of Iran, IRN) ,  DAI Hongmei (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  DAI Hongmei (Dep. of Pediatrics, Tohoku Univ. School of Medicine, JPN) ,  KATO Motohisa (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  XU Ajing (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  OKUDA Tomohiro (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  SAKURAI Eiko (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  OKAMURA Nobuyuki (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN) ,  TAKAHASHI Kazuhiro (Dep. of Endocrinology and Applied Medical Sci., Tohoku Univ. School of Medicine, JPN) ,  YANAI Kazuhiko (Dep. of Pharmacology, Tohoku Univ. School of Medicine, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 107  Issue： 2  Page： 167-174 (J-STAGE)  Publication year： 2008 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...

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JST classification (3)： Basic research of psychotropic drugs  (GW03100Y) ,  Basic neurology  (GN01020W) ,  Basic psychiatry  (GR01020I)

Substance index (5)： Clozapine ,  Thioperamide ,  Donepezil ,  Mepyramine ,  Methamphetamine

Reference (31)：

• 1 Watanabe T, Taguchi Y, Shiosaka S, Tanaka J, Kubota H, Terano Y, et al. Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker. Brain Res. 1984;295:13–25.
• 2 Yanai K, Son LZ, Endou M, Sakurai E, Nakagawasai O, Tadano T, et al. Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors. Neuroscience. 1998;87:479–487.
• 3 Yanai K, Watanabe T. Histamine as a neurotransmitter in the central nervous system. In: Falus A, Grosman N, Darvas Zs, editors. Histamine: biology and medical aspects. SpringMed Publishing and S. Karger AG; 2004. p. 251–263.
• 4 Kuramasu A, Sukegawa J, Yanagisawa T, Yanai K. Recent advances in molecular pharmacology of the histamine systems: roles of C-terminal tails of histamine receptors. J Pharmacol Sci. 2006;101:7–11.
• 5 Yanai K, Okamura N, Tagawa M, Itoh M, Watanabe T. New findings in pharmacological effects induced by antihistamines: from PET studies to knock-out mice. Clin Exp Allergy. 1999;29 Suppl 3:29–36.

Terms in the title (7)： ヒスタミン ,  阻害 ,  社会的隔離 ,  メタンフェタミン ,  反復投与 ,  マウス ,  学習と記憶障害