Art

J-GLOBAL ID：200902227726668775   Reference number：08A1072393

TRPA1 Agonists-Allyl Isothiocyanate and Cinnamaldehyde-Induce Adrenaline Secretion

TRPA1作動薬のイソチオシアン酸アリルとシンナムアルデヒドはアドレナリン分泌を誘起する

Author (4)： IWASAKI Yusaku (Graduate School of Nutritional and Environmental Sciences and Global COE Program, Univ. of Shizuoka) ,  TANABE Manabu (Graduate School of Nutritional and Environmental Sciences and Global COE Program, Univ. of Shizuoka) ,  KOBATA Kenji (Graduate School of Nutritional and Environmental Sciences and Global COE Program, Univ. of Shizuoka) ,  WATANABE Tatsuo (Graduate School of Nutritional and Environmental Sciences and Global COE Program, Univ. of Shizuoka)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 72  Issue： 10  Page： 2608-2614 (J-STAGE)  Publication year： 2008 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Ion Channels ,...
Semi thesaurus term： TRPA1作動薬

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JST classification (2)： Influence on animals  (EE05040R) ,  Physiology and anatomy of endocrine system  (EJ08000J)

Substance index (4)： Epinephrine ,  Allyl isothiocyanate ,  Capsaicin ,  Cinnamaldehyde

Reference (38)：

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• 2) Bandell, M., Story, G. M., Hwang, S. W., Viswanath, V., Eid, S. R., Petrus, M. J., Earley, T. J., and Patapoutian, A., Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron, 41, 849–857 (2004).
• 3) Macpherson, L. J., Geierstanger, B. H., Viswanath, V., Bandell, M., Eid, S. R., Hwang, S., and Patapoutian, A., The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr. Biol., 15, 929–934 (2005).
• 4) Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., and Julius, D., The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 389, 816–824 (1997).
• 5) McNamara, F. N., Randall, A., and Gunthorpe, M. J., Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br. J. Pharmacol., 144, 781–790 (2005).

Terms in the title (7)： TRPA1 ,  作動薬 ,  イソチオシアン酸アリル ,  シンナムアルデヒド ,  アドレナリン ,  分泌 ,  誘起