Art

J-GLOBAL ID：200902230188725934   Reference number：04A0329891

Blocking of Human Immunodeficiency Virus Type-1 Virion Autolysis by Autologous p2^gag Peptide

自己p2^gagペプチドによるHIV1ビリオン自己分解の阻止

Author (6)： MISUMI S (Kumamoto Univ., Kumamoto, JPN) ,  MORIKAWA Y (Kumamoto Univ., Kumamoto, JPN) ,  TOMONAGA M (Kumamoto Univ., Kumamoto, JPN) ,  OHKUMA K (Kumamoto Univ., Kumamoto, JPN) ,  TAKAMUNE N (Kumamoto Univ., Kumamoto, JPN) ,  SHOJI S (Kumamoto Univ., Kumamoto, JPN)
Material： Journal of Biochemistry  (J Biochem)
Volume： 135  Issue： 3  Page： 447-453  Publication year： Mar. 01, 2004 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *HIV ,...
Semi thesaurus term： T lymphocyte ,...

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JST classification (2)： Biological function  (EB03040U) ,  Virus biochemistry  (EG04030F)

Substance index (2)： p2^gag Peptide ,  Nona p2^gag peptide

Reference (29)：

• KOHL, N. E. Active human immunodeficiency virus protease is required for viral infectivity. Proc. Natl Acad. Sci. USA. 1988, 85, 4686-4690
• VAISHNAV, Y. N. The biochemistry of AIDS. Annu. Rev. Biochem. 1991, 60, 577-630
• MISUMI, S. The p2^<gag> peptide, AEAMSQVTNTATIM, processed from HIV-1 Pr55^<gag> was found to be a suicide inhibitor of HIV-1 protease. Biochem. Biophys. Res. Commun. 1997, 241, 275-280
• KONVALINKA, J. An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR mediated cytotoxicity without apparent effect on virus maturation and infectivity. J. Virol. 1995, 69, 7180-7186
• LAYNE, S. P. Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus. Virology. 1992, 189, 695-714

Terms in the title (6)： 自己 ,  ペプチド ,  HIV1 ,  ビリオン ,  自己分解 ,  阻止