Art

J-GLOBAL ID：200902233496847888   Reference number：03A0620521

Extract of Cassia nomame has effect on the cell cycle of CHO-K1 cells and suppresses chromosome aberrations induced by Mitomycin C

Cassia nomameのエキスはCHO-K1細胞の細胞周期に作用し,マイトマイシンCで誘導した染色体異常を抑制する

Author (4)： KADOWAKI S (Nagaoka Univ. Technol., Niigata, JPN) ,  NAITOU K (Nagaoka Univ. Technol., Niigata, JPN) ,  TAKAHARA Y (Nagaoka Univ. Technol., Niigata, JPN) ,  YAMAMOTO K (Nagaoka Univ. Technol., Niigata, JPN)
Material： Journal of Traditional Medicines  (和漢医薬学雑誌)
Volume： 20  Issue： 4  Page： 168-172  Publication year： Aug. 20, 2003 
JST Material Number： Y0941A  ISSN： 1880-1447  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Cassia ,...
Semi thesaurus term： Cassia nomame

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JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Molecular genetics in general  (EC02010J)

Substance index (1)： Mitomycin

Reference (4)：

• MENGS, U. No clastogenic activity of a senna extract in the mouse micronucleus assay. Mutat. Res. 1999, 444, 421-426
• KADOWAKI, S. The suppressing effect of the extract from Cassia nomame on clastogenicity and cytotoxicity of Mitomycin C in CHO cells. J. Health Sci. 2001, 47, 1, 86-88
• MEYN, R. E. Evaluation of S phase synchronization by analysis of DNA replication in 5-bromodeoxyuridine. Exp. Cell Res. 1973, 82, 137-142
• SASAKI, Y. F. Suppressing effect of tannic acid on the frequencies of mutagen-induced sister-chromatid exchanges in mammalian cells. Mutat. Res. 1989, 213, 195-203

Terms in the title (7)： Cassia ,  エキス ,  CHO-K1細胞 ,  細胞周期 ,  マイトマイシンC ,  誘導 ,  染色体異常