Art

J-GLOBAL ID：200902235391348838   Reference number：09A0655763

In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes

ヒトの人工多能性幹細胞由来の心筋細胞を用いたin vitroにおける薬理学的試験

Author (22)： TANAKA Tomofumi (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  TANAKA Tomofumi (Biomedical Res. Laboratories, Asubio Pharma Co., Ltd, Osaka, JPN) ,  TOHYAMA Shugo (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  TOHYAMA Shugo (Cardiology Div., School of Medicine, Keio Univ., Tokyo, JPN) ,  MURATA Mitsushige (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  NOMURA Fumimasa (Dep. of Biomedical Information, Inst. of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., Tokyo, JPN) ,  KANEKO Tomoyuki (Dep. of Biomedical Information, Inst. of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., Tokyo, JPN) ,  CHEN Hao (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  HATTORI Fumiyuki (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  HATTORI Fumiyuki (Biomedical Res. Laboratories, Asubio Pharma Co., Ltd, Osaka, JPN) ,  EGASHIRA Toru (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  EGASHIRA Toru (Cardiology Div., School of Medicine, Keio Univ., Tokyo, JPN) ,  SEKI Tomohisa (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  SEKI Tomohisa (Cardiology Div., School of Medicine, Keio Univ., Tokyo, JPN) ,  OHNO Yohei (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  OHNO Yohei (Cardiology Div., School of Medicine, Keio Univ., Tokyo, JPN) ,  KOSHIMIZU Uichi (Biomedical Res. Laboratories, Asubio Pharma Co., Ltd, Osaka, JPN) ,  YUASA Shinsuke (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN) ,  OGAWA Satoshi (Cardiology Div., School of Medicine, Keio Univ., Tokyo, JPN) ,  YAMANAKA Shinya (Dep. of Stem Cell Biology, Inst. for Frontier Medical Sciences, Kyoto Univ., Kyoto, JPN) ,  YASUDA Kenji (Dep. of Biomedical Information, Inst. of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., Tokyo, JPN) ,  FUKUDA Keiichi (Dep. of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio Univ., Tokyo, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 385  Issue： 4  Page： 497-502  Publication year： Aug. 07, 2009 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： human ,  *stem cell ,  *cultured cell ,  *screening (inspection) ,  *Cardiac Myocyte ,  ANP ,  Proteins ,  transcription factor ,  DNA binding protein ,  Ion Channels ,  electrophysiology ,  *drug ,  *induced pluripotent stem cell ,  GATA4 Transcription Factor ,  Nkx2-5 protein ,  Ion Transport ,  transportation ,  Biological Transport ,  transmembrane protein ,  ion transport(in vivo)
Semi thesaurus term： GATA-4 ,  Nkx2-5 ,  ANP

JST classification (2)： Research methods in biological sciences in general  (EA03010K) ,  Heart  (EJ04020D)

Terms in the title (5)： ヒト ,  人工多能性幹細胞 ,  心筋細胞 ,  薬理学 ,  試験