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J-GLOBAL ID:200902236746367118
Reference number:09A0070900
Comparison of alternate-day versus consecutive-day treatment with S-1: assessment of tumor growth inhibition and toxicity reduction in gastric cancer cell lines in vitro and in vivo
S-1での隔日vs連日治療の比較 in vitroおよびin vivoでの胃癌細胞株の腫瘍増殖阻害および毒性減少の評価
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Material:
Volume:
13
Issue:
6
Page:
515-520
Publication year:
Dec. 2008
JST Material Number:
L3966A
ISSN:
1341-9625
Document type:
Article
Article type:
原著論文
Country of issue:
Germany, Federal Republic of (DEU)
Language:
ENGLISH (EN)
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Basic research of antitumor(=antineoplastic)drugs
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Reference (26):
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SHIRASAKA, T. Development of a novel form of 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs. 1996, 7, 548-557
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SHIRASKA, T. Conceptual changes in cancer chemotherapy : from an oral fluoropyrimidene prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan. Invest New Drugs. 2000, 18, 315-329
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TATSUMI, K. Inhibitory effects of pyrimidine, barbituric acid and pyrimidine derivatives on 5-fluorouracil degradation in rat liver extracts. Jpn J Cancer Res. 1987, 78, 748-755
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SHIRASAKA, T. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993, 53, 4004-4009
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SAKATA, Y. Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients. Eur J Cancer. 1998, 34, 1715-1720
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