Art

J-GLOBAL ID：200902239583227037   Reference number：05A0877444

Synthesis of Linear Tripeptides for Right-Hand Segments of Complestatin

コンプレスタチンの右側セグメント用の直線状トリペプチドの合成

Author (10)： YAMADA Yaeko (School of Pharmaceutical Sciences, Kitasato Univ.) ,  AKIBA Ai (School of Pharmaceutical Sciences, Kitasato Univ.) ,  ARIMA Shiho (School of Pharmaceutical Sciences, Kitasato Univ.) ,  OKADA Chiharu (School of Pharmaceutical Sciences, Kitasato Univ.) ,  YOSHIDA Kiminari (School of Pharmaceutical Sciences, Kitasato Univ.) ,  ITOU Fumihiro (School of Pharmaceutical Sciences, Kitasato Univ.) ,  KAI Toshitsugu (School of Pharmaceutical Sciences, Kitasato Univ.) ,  SATOU Toshiko (School of Pharmaceutical Sciences, Kitasato Univ.) ,  TAKEDA Kazuyoshi (Center for Advanced Technol., Ebara Res. Co., Ltd.) ,  HARIGAYA Yoshihiro (School of Pharmaceutical Sciences, Kitasato Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 53  Issue： 10  Page： 1277-1290 (J-STAGE)  Publication year： 2005 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *tripeptide ,...
Semi thesaurus term： bridged compound

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JST classification (2)： Peptides  (CF10080G) ,  Eight or more-membered heterocyclic compounds  (CF07120T)

Substance index (24)： Complestatin ,  Chloropeptin I ,  (3R,6R,9R)-3-(Benzyloxycarbonylamino)-4,7-dioxo-6-(3,5-dichloro-4-methoxyphenyl)-12-iodo-13-methoxy-10,14:15,19-dimetheno-5,8,20-triazabicyclo[16.3.0]henicosa-10,12,15,17,21(1)-pentaene-9-carboxylic acid methyl ester ,  N-[(R)-2-(Benzyloxycarbonylamino)-3-[6-[2-methoxy-3-iodo-5-[(R)-1-amino-2-oxo-2-methoxyethyl]phenyl]-1H-indole-3-yl]propionyl]-3,5-dichloro-4-methoxy-D-phenylglycine ,  N^α-(Benzyloxycarbonyl)-6-[2-methoxy-3-iodo-5-[(R)-1-[2-amino-2-(3,5-dichloro-4-methoxyphenyl)acetylamino]-2-oxo-2-methoxyethyl]phenyl]-L-tryptophan ,  Z-6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolane-2-yl)-D-Trp-3,5-dichloro-4-methoxy-D-phenyl Gly-3,5-diiodo-4-methoxy-D-phenyl Gly-OMe ,  Z-6-(Tributylstannyl)-D-Trp-3,5-dichloro-4-methoxy-D-phenyl Gly-3,5-diiodo-4-methoxy-D-phenyl Gly-OMe ,  6-Nitroindoline ,  6-Iodo-N^α-(benzyloxycarbonyl)-D-tryptophan ,  4-Hydroxy-D-phenylglycine ,  3,5-Diiodo-4-hydroxy-D-phenylglycine ,  N-(tert-Butoxycarbonyl)-2-(3,5-diiodo-4-methoxyphenyl)-D-Gly-OMe ,  N-(tert-Butoxycarbonyl)-3-iodo-4-methoxy-5-(tributylstannyl)-D-phenylglycine methyl ester ,  3,5-Dichloro-4-hydroxy-D-phenylglycine ,  3,5-Dichloro-4-hydroxy-D-phenylglycine tert-butyl ester ,  Z-6-Iodo-D-Trp-3,5-dichloro-4-methoxy-D-phenyl Gly-OBu^t ,  N^α-(Benzyloxycarbonyl)-6-iodo-D-tryptophan tert-butyl ester ,  N^α-(Benzyloxycarbonyl)-6-[2-methoxy-3-iodo-5-[(R)-1-amino-2-oxo-2-methoxyethyl]phenyl]-D-tryptophan tert-butyl ester ,  3,5-Diiodo-4-hydroxy-D-phenylglycine methyl ester ,  N-(tert-Butoxycarbonyl)-3,5-dichloro-4-hydroxy-D-phenylglycine ,  Boc-3,5-Dichloro-4-methoxy-D-phenyl Gly-3,5-diiodo-4-methoxy-D-phenyl Gly-OMe ,  N^α-(Benzyloxycarbonyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-D-tryptophan ,  3,5-Dichloro-4-methoxy-D-phenyl Gly-3,5-diiodo-4-methoxy-D-phenyl Gly-OMe ,  N^α-(Benzyloxycarbonyl)-6-(tributylstannyl)-D-tryptophan sodium salt

Reference (37)：

• 1) Kaneko I., Fearon D. T., Austen K., J. Immunol., 124, 1194—1198 (1980).
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Terms in the title (5)： コンプレスタチン ,  右側 ,  セグメント ,  直線状 ,  トリペプチド