High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: A cancer-prone animal model

TSUDA Hiroyuki; FUKAMACHI Katsumi; OHSHIMA Yutaka; UEDA Shinobu; MATSUOKA Yoichiro; HAMAGUCHI Tetsuya; OHNISHI Takamasa; TAKASUKA Nobuo; NAITO Akihiro

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J-GLOBAL ID：200902239645382069 Reference number：05A0621408

High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: A cancer-prone animal model

ヒトc-Ha-rasプロト発癌遺伝子トランスジェニックラットの発癌性に対する高い感受性癌になりやすい動物モデル

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Material：
Volume： 96 Issue： 6 Page： 309-316 Publication year： Jun. 2005
JST Material Number： W1423A ISSN： 1347-9032 Document type： Article
Article type：文献レビュー Country of issue： Australia (AUS) Language： ENGLISH (EN)

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Laboratry organisms , Gene manipulation , Carcinogenic mechanisms and factors

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Reference (63)：

USUI, T. CB6F1-rasH2 mouse : overview of available data. Toxicol Pathol. 2001, 29, Suppl., 90-108
TAMAOKI, N. The rasH2 transgenic mouse : nature of the model and mechanistic studies on tumorigenesis. Toxicol Pathol. 2001, 29, Suppl., 81-89
ANDO, K. Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes. Cancer Res. 1992, 52, 978-982
TENNANT, RW. The Tg.AC (v-Ha-ras) transgenic mouse : nature of the model. Toxicol Pathol. 2001, 29, Suppl., 51-59
SPALDING, JW. Chemically induced skin carcinogenesis in a transgenic mouse line (Tg.AC) carrying a v-Ha-ras gene. Carcinogenesis. 1993, 14, 1335-1341

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