Purification and Characterization of Recombinant Human Prostacyclin Synthase

WADA M; YOKOYAMA C; HATAE T; SHIMONISHI M; NAKAMURA M; IMAI Y; ULLRICH V; TANABE T

Art

J-GLOBAL ID：200902240378308065 Reference number：04A0423183

Purification and Characterization of Recombinant Human Prostacyclin Synthase

組換ヒトプロスタサイクリンシンターゼの精製及び特性化

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Volume： 135 Issue： 4 Page： 455-463 Publication year： Apr. 01, 2004
JST Material Number： F0286A ISSN： 0021-924X CODEN： JOBIAO Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Enzyme in general , Gene manipulation

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Reference (42)：

MONCADA, S. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature. 1976, 263, 663-665
MONCADA, S. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol. Rev. 1978, 30, 293-331
NEGISHI, M. Molecular mechanisms of diverse actions of prostanoid receptors. Biochim. Biophys. Acta. 1995, 1259, 109-119
FORMAN, B. M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc. Natl Acad. Sci. USA. 1997, 94, 4312-4317
GUPTA, R. A. Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc. Natl. Acad. Sci. USA. 2000, 97, 13275-13280

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