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J-GLOBAL ID：200902242785924440   Reference number：05A0685086

Eleven New 2-Pyrones from a Fungi Imperfecti, Trichurus terrophilus, Found in a Screening Study Guided by Immunomodulatory Activity

免疫調節活性を指標とするスクリーニング研究で見いだされた不完全菌類,Trichurus terrophilusからの11種の新しい2-ピロン類

Author (6)： FUJIMOTO Haruhiro (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  OKAMOTO Yoshie (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  SONE Eriko (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  MAEDA Satomi (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  AKIYAMA Kohki (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  ISHIBASHI Masami (Graduate School of Pharmaceutical Sciences, Chiba Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 53  Issue： 8  Page： 923-929 (J-STAGE)  Publication year： 2005 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *lactone ,...
Semi thesaurus term： Trichurus terrophilus

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JST classification (2)： Pyranes  (CF07092R) ,  Microorganism biochemistry  (EG03020N)

Substance index (11)： Rasfonin ,  Trichurusin B ,  Trichurusin C ,  Trichurusin D ,  Trichurusin E ,  Trichurusin F ,  Trichurusin G ,  (2E,4E,6S)-4-Methyl-6-(hydroxymethyl)-8-acetoxy-2,4-octadienoic acid (2R)-2α-[(1S,3R)-1,3-dimethyl-4-(2,3-dimethyloxiranyl)butyl]-6-oxo-3,6-dihydro-2H-pyran-3α-yl ester ,  Trichurusin J ,  Trichurusin K ,  (2E,4E,6S)-4-Methyl-6-(acetoxymethyl)-8-acetoxy-2,4-octadienoic acid (2R)-2α-[(1S,3R,5E)-1,3,5-trimethyl-5-heptenyl]-6-oxo-3,6-dihydro-2H-pyran-3α-yl ester

Reference (9)：

• 1) Present address: Faculty of Pharmaceutical Sciences, Teikyo Heisei University; 2289–23 Uruido, Ichihara, Chiba 290–0193, Japan. E-mail: [e-mail]
• 2) Fujimoto H., Nakamura E., Okuyama E., Ishibashi M., Chem. Pharm. Bull., 52, 1005—1008 (2004), and the references cited therein.
• 3) This strain was deposited earlier at Research Institute for Chemobiodynamics, Chiba University (present name: Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University). A voucher specimen is also on deposit in our laboratory.
• 4) Ishii H., Seo S., Tori K., Tozyo T., Yoshimura Y., Tetrahedron Lett., 1977, 1227—1230 (1997).
• 5) Tori K., “Kagaku No Ryoiki Zokan,” Vol. 125, Nankodo, Tokyo, 1980, pp. 221—245.

Terms in the title (6)： 免疫調節活性 ,  指標 ,  スクリーニング ,  研究 ,  不完全菌類 ,  2-ピロン