Art

J-GLOBAL ID：200902244151640867   Reference number：04A0339877

研究成果と臨床応用 口腔乾燥症状改善薬の開発研究

Author (1)： IWABUCHI YOSHIKI (日本歯大 新潟歯 薬理学)
Material： 歯学 特集号  (特集号 歯学)
Volume： 91  Issue： 春季  Page： 125-130  Publication year： Mar. 20, 2004 
JST Material Number： L4779A  ISSN： 0029-8484  CODEN： SHIGAZ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： rat ,...

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JST classification (3)： Basic research of drugs acting on digestive system  (GW09010Q) ,  Basic medicine on digestive system  (GH01020E) ,  Treatment for diseases of tooth and mouth(=oral cavity)in general  (GT05010F)

Substance index (1)： Cevimeline

Reference (16)：

• VIVINO, FB. Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjogren syndrome. Arch Intern Med. 1999, 159, 174-181
• VARDEZ, IH. Use of pilocarpine during head and neck radiation therapy to reduce xerostomia and salivary dysfunction. Cancer. 1993, 71, 1848-1851
• WISEMAN, LR. Oral pilocarpine : A review of its pharmacological properties and clinical potential in xerostomia. Drugs. 1995, 49, 143-155
• IWABUCHI, Y. Sialogogic activities of SNI-2011compared with those of pilocarpine and McN-A-343 in rat salivary glands : Identification of a potential therapeutic agent for treatment of Sjogren's syndrome. Gen Pharmacol. 1994, 25, 123-129
• IGA, Y. (±)-cis-2-Methylspiro [1,3-oxathiolane-5,3-quinuclidine] hydrochloride, hemihydrate (SNI-2011, cevimeline hydrochloride) induces saliva and tear secretions in rats and mice : The role of muscarinic acetyl-choline receptors. Jap J Pharmacol. 1998, 78, 373-380

Terms in the title (6)： 研究 ,  成果 ,  臨床 ,  応用 ,  口腔乾燥症 ,  開発