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J-GLOBAL ID：200902244327373011   Reference number：08A0038668

Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1

ヒト胃癌細胞株MKN-1におけるRUNX3遺伝子導入により誘導したアポトーシス経路

Author (11)： NAGAHAMA Yumi (Tottori Univ., Tottori) ,  ISHIMARU Mika (Tottori Univ., Tottori) ,  OSAKI Mitsuhiko (Tottori Univ., Tottori) ,  INOUE Toshiaki (Tottori Univ., Tottori) ,  MAEDA Akihiro (Tottori Univ., Tottori) ,  NAKADA Chisato (Tottori Univ., Tottori) ,  NAKADA Chisato (Oita Univ., Oita, JPN) ,  MORIYAMA Masatsugu (Oita Univ., Oita, JPN) ,  SATO Kenzo (Tottori Univ., Tottori) ,  OSHIMURA Mitsuo (Tottori Univ., Tottori) ,  ITO Hisao (Tottori Univ., Tottori)
Material： Cancer Science  (Cancer Sci)
Volume： 99  Issue： 1  Page： 23-30  Publication year： Jan. 2008 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： stomach tumor ,...
Semi thesaurus term： LacZ gene ,...

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JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (1)： Doxycycline

Reference (39)：

• LEAVANON, D. A large variety of alternatively spliced and differentially expressed mRNAs are encoded by the human acute myeloid leukemia gene AML1. DNA Cell Biol. 1996, 15, 175-185
• ITO, Y. Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP/CBF. Gene Cells. 1999, 4, 685-696
• BANGSOW, C. The RUNX3 gene-sequence, structure and regulated expression. Gene. 2001, 279, 221-232
• LI, QL. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 2002, 109, 113-124
• WAKI, T. Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia. Cancer Sci. 2003, 94, 360-364

Terms in the title (7)： ヒト ,  胃 ,  癌細胞株 ,  RUNX3遺伝子 ,  誘導 ,  アポトーシス ,  経路