Art

J-GLOBAL ID：200902246230526967   Reference number：03A0525601

A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes.

変異原性/発癌性アミノ-又はニトロ-アレーンの2′-デオキシグアノシン-C8付加化合物の実用的な化学合成法

Author (4)： TAKAMURA-ENYA T (National Cancer Center Res. Inst., Tokyo, JPN) ,  ISHIKAWA S (Kyoritu Coll. Pharmacy, Tokyo, JPN) ,  MOCHIZUKI M (Kyoritu Coll. Pharmacy, Tokyo, JPN) ,  WAKABAYASHI K (National Cancer Center Res. Inst., Tokyo, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 44  Issue： 32  Page： 5969-5973  Publication year： Aug. 04, 2003 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *nucleoside analog ,...

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JST classification (1)： Nucleosides,nucleotides  (CF10060K)

Substance index (20)： 1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-bromo-9H-purine-9-yl]-1,2-dideoxy-β-D-erythro-pentofuranose 3,5-diacetate ,  Trimethylsilyl azide ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-azido-9H-purine-9-yl]-1,2-dideoxy-β-D-erythro-pentofuranose 3,5-diacetate ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-amino-9H-purine-9-yl]-3-O,5-O-bis(tert-butyldimethylsilyl)-1,2-dideoxy-β-D-erythro-pentofuranose ,  4-Bromobiphenyl ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-(4-biphenylylamino)-9H-purine-9-yl]-3-O,5-O-bis(tert-butyldimethylsilyl)-1,2-dideoxy-β-D-erythro-pentofuranose ,  Xantphos ,  2-Bromonaphthalene ,  2-Bromo-9H-fluorene ,  1-Bromopyrene ,  3-Bromobenzanthrone ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-(2-naphthylamino)-9H-purine-9-yl]-3-O,5-O-bis(tert-butyldimethylsilyl)-1,2-dideoxy-β-D-erythro-pentofuranose ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-(1-pyrenylamino)-9H-purine-9-yl]-3-O,5-O-bis(tert-butyldimethylsilyl)-1,2-dideoxy-β-D-erythro-pentofuranose ,  1-[2-(4-Methoxytritylamino)-6-(benzyloxy)-8-(9H-fluorene-2-ylamino)-9H-purine-9-yl]-3-O,5-O-bis(tert-butyldimethylsilyl)-1,2-dideoxy-β-D-erythro-pentofuranose ,  3-[2-(4-Methoxytritylamino)-6-(benzyloxy)-9-[3-O,5-O-bis(tert-butyldimethylsilyl)-2-deoxy-β-D-erythro-pentofuranosyl]-9H-purine-8-ylamino]-7H-benzo[de]anthracene-7-one ,  8-(4-Biphenylylamino)guanosine ,  8-(2-Naphthylamino)guanosine ,  8-(1-Pyrenylamino)guanosine ,  8-(9H-Fluorene-2-ylamino)guanosine ,  8-(7-Oxo-7H-benzo[de]anthracene-3-ylamino)guanosine

Terms in the title (7)： 変異原性 ,  発癌性 ,  アレーン ,  2′-デオキシグアノシン ,  C8 ,  付加化合物 ,  化学合成法