Art

J-GLOBAL ID：200902248514502300   Reference number：03A0652160

Antiviral Activity of 2-Amino-4,4α-Dihydro-4α-7-Dimethyl-3H-Phenoxazine-3-One on Poliovirus

ポリオウイルスに対する2-アミノ-4,4α-ジヒドロ-4α-7-ジメチル-3H-フェノキサジン-3-オンの抗ウイルス活性

Author (5)： IWATA A (National Inst. of Health Sci., Tokyo) ,  YAMAGUCHI T (National Inst. of Health Sci., Tokyo) ,  SATO K (Inst. of Saitama Red Cross Center, Kumagaya) ,  IZUMI R (National Space Dev. Agency of Japan (NASDA), Tsukuba) ,  TOMODA A (Tokyo Medical Univ., Tokyo)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 200  Issue： 3  Page： 161-165  Publication year： Jul. 2003 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,...
Semi thesaurus term： *polio virus ,...

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JST classification (1)： Basic research of antiviral drugs  (GW17040O)

Substance index (1)： PHEX-5

Reference (22)：

• Abe, A., Yamane, M. & Tomoda, A. (2001) Prevention of growth of human lung carcionma cells and induction of apoptosis by a novel phenoxazine, 2-amino-4, 4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one. <i>Anti-Cancer Drugs</i>, <b>12</b>, 377-382.
• Akazawa, M., Koshibu-Koizumi, J., Iwamoto, T., Takasaki, M., Nakamura, M. & Tomoda, A. (2002) Effects of novel phenoxazine compounds, 2-amino-4, 4α-dihydro-4α-7-dime-thyl-3H-phenoxazine-3-one and 3-amino-1, 4α-di-hydro-4α-8-dimethyl-2H-phenoxazine-2-one on pro-liferation of phytohemagglutinin- or anti-human IgM-activated human peripheral blood mononuclear cells. <i>Tohoku J. Exp. Med</i>., <b>196</b>, 185-192.
• Andersen, D.O., Weber, N.D., Wood, S.G., Hughes, B.G., Murray, B.K. & North, J.A. (1991) In vitro virucidal activity of selected anthra-quinones and anthraquinone derivatives. <i>Antiviral Res</i>., <b>16</b>, 185-196.
• Gao, S., Takano, T., Sada, K., He, J., Noda, C., Hori-Tamura, N., Tomoda, A. & Yamamura, H. (2002) A novel phenoxazine derivative suppresses surface IgM expression in DT40 B cell line. <i>Br. J. Pharmacol</i>., <b>137</b>, 749-755.
• Goldberg, I.H. & Friedman, P.A. (1971) Antibiotics and nucleic acids. <i>Annu. Rev. Biochem</i>., <b>40</b>, 775-810.

Terms in the title (3)： ポリオウイルス ,  ジメチル ,  抗ウイルス活性