Art

J-GLOBAL ID：200902249321341420   Reference number：08A0188320

Isolation of Apoptosis- and Differentiation-Inducing Substances toward Human Promyelocytic Leukemia HL-60 Cells from Leaves of Juniperus taxifolia

オキナワハイネズ(Juniperus taxifolia)の葉由来のヒト前骨髄球白血病HL-60細胞へのアポプトシスおよび分化誘導物質の単離

Author (8)： MUTO Norio (Fac. of Life and Environmental Sciences, Prefectural Univ. of Hiroshima) ,  TOMOKUNI Tatsuru (School of Bioresources, Hiroshima Prefectural Univ.) ,  HARAMOTO Mari (Fac. of Life and Environmental Sciences, Prefectural Univ. of Hiroshima) ,  TATEMOTO Hideki (Fac. of Agriculture, Univ. of the Ryukyus) ,  NAKANISHI Tsutomu (Fac. of Pharmaceutical Sciences, Setsunan Univ.) ,  INATOMI Yuka (Fac. of Pharmaceutical Sciences, Setsunan Univ.) ,  MURATA Hiroko (Fac. of Pharmaceutical Sciences, Setsunan Univ.) ,  INADA Akira (Fac. of Pharmaceutical Sciences, Setsunan Univ.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 72  Issue： 2  Page： 477-484 (J-STAGE)  Publication year： 2008 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： leaf ,  human ,  isolation (separation) ,  diterpene ,  cytotoxicity ,  DNA ,  Apoptosis ,  *Juniperus ,  *HL60 cell ,  Leukemia ,  Cell Proliferation ,  Cell Differentiation ,  aliphatic chlorine compound ,  trihalomethane ,  educt ,  DNA Fragmentation ,  differentiation (biology) ,  developmental physiology
Semi thesaurus term： DNA fragmentation ,  hplHL-60細胞 ,  *Juniperus taxifolia ,  *オキナワハイネズ ,  前骨髄球白血病 ,  dosage dependence

JST classification (1)： Plant biochemistry  (EH01050J)

Substance index (3)： 7α-Hydroxysadaracopimaric acid ,  Chloroform ,  Deoxypodophyllotoxin

Reference (32)：

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• BACCARANI, M. Differentiation of myeloid leukaemic cells : new possibilities for therapy. Br. J. Haematol. 1979, 42, 485-487
• HOUSSET, M. Small doses of ARA-C in the treatment of acutemyeloid leukemia cells?. Br. J. Haematol. 1982, 51, 125-129
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• PARKINSON, D. R. Trans-retinoic acid and related differentiation agents. Semin. Oncol. 1992, 19, 734-741

Terms in the title (8)： Juniperus ,  葉 ,  ヒト ,  白血病 ,  HL-60細胞 ,  アポプトシス ,  分化 ,  単離