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J-GLOBAL ID：200902249770215897   Reference number：05A0760518

Biological Significance of Isoaspartate and Its Repair System

イソアスパラギン酸の生物学的意義とその修復機構

Author (3)： SHIMIZU Takahiko (Res. Team for Molecular Biomarkers, Tokyo Metropolitan Inst. of Gerontology) ,  MATSUOKA Yasuji (Center for Dementia Res., Nathan Kline Inst. for Psychiatric Res. and Dep. of Psychiatry, New York Univ. School of ...) ,  SHIRASAWA Takuji (Res. Team for Molecular Biomarkers, Tokyo Metropolitan Inst. of Gerontology)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 28  Issue： 9  Page： 1590-1596 (J-STAGE)  Publication year： 2005 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *amino acid ,...
Semi thesaurus term： chemical structure ,...

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JST classification (4)： Amino acids  (CF10070V) ,  Biological function  (EB03040U) ,  Enzyme physiology  (EJ02020P) ,  Basic neurology  (GN01020W)

Substance index (5)： Succinimide ,  Asparagine ,  Aspartic Acid ,  Proline ,  2-Amino-2-methylpropanedioic acid

Reference (86)：

• 1) Present address: Department of Neurology, Georgetown University Medical Center, 4000 Reservoir Rd. N.W., Washington, DC 20057, U.S.A.
• 2) Lindner H., Helliger W., Exp. Gerontol., 36, 1551—1563 (2001).
• 3) Clarke S., Ageing Res. Rev., 2, 263—285 (2003).
• 4) Geiger T., Clarke S., J. Biol. Chem., 262, 785—794 (1987).
• 5) Brennan T. V., Clarke S., “Deamidation and Isoaspatate Fomation in Peptides and Proteins,” ed. by Aswad D. W., CRC Press, Boca Raton, 1995, pp. 65—90.

Terms in the title (3)： イソアスパラギン酸 ,  生物学 ,  修復