Art

J-GLOBAL ID：200902249853840653   Reference number：09A0067650

Development of an LC-ESI-MS/MS method for the determination of histamine: Application to the quantitative measurement of histamine degranulation by KU812 cells

ヒスタミンの定量用LC-ESI-MS/MS法の開発:KU812細胞によるヒスタミン脱顆粒の定量的測定への適用

Author (8)： KOYAMA Junko (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN) ,  TAKEUCHI Atsuko (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN) ,  TODE Chisato (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN) ,  SHIMIZU Maki (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN) ,  MORITA Izumi (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN) ,  NOBUKAWA Machiko (School of Allied Health Sciences, Kitasato Univ., Sagamihara 228-8555, JPN) ,  NOBUKAWA Makiko (Tokai Univ. Tokyo Hospital, Shibuya, Yoyogi, Tokyo 151-0053, JPN) ,  KOBAYASHI Norihiro (Kobe Pharmaceutical Univ., Higashinada, Kobe 658-8558, JPN)
Material： Journal of Chromatography B  (Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences)
Volume： 877  Issue： 3  Page： 207-212  Publication year： Jan. 15, 2009 
JST Material Number： W0571A  ISSN： 1570-0232  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *degranulation (immunology) ,  *LC-MS analysis ,  *Tandem Mass Spectrometry ,  basophilic ,  antiallergic agent ,  in vitro experiment ,  quantitative analysis (analytical chemistry) ,  tumor cell ,  cultured cell ,  electrospray ionization ,  internal standard method ,  chromatographic column ,  elution ,  retention time ,  standard deviation ,  Taxus ,  nitrogen heterocyclic compound ,  primary amine ,  alcohol ,  oxygen heterocyclic compound ,  carboxylate (salt) ,  phenol ether ,  polynuclear aromatic compound ,  keto acid ,  KU812 cell ,  isocratic elution ,  Taxus yunnanensis ,  *liquid chromatography-tandem mass spectrometry ,  autacoid
Semi thesaurus term： *LC/MS/MS

JST classification (2)： Miscellaneous analytical methods of organic compounds  (CC08034J) ,  Analysis of drugs  (GV01040Q)

Substance index (5)： Histamine ,  Isotaxiresinol ,  Pyrazole ,  Cromolyn sodium ,  Taxiresinol

Reference (32)：

• BEASLEY, R. Lancet. 1998, 351, 1225
• WILLIAMS, H. J. Allergy Clin. Immunol. 1999, 103, 125
• HOLGATE, S. T. Nature. 1999, 402, B2
• KIM, C. D. Int. Immunopharmacol. 2003, 3, 129
• LEE, J. H. J. Pharm. Pharmacol. 2004, 56, 927

Terms in the title (7)： ヒスタミン ,  定量 ,  LC-ESI-MS ,  MS法 ,  開発 ,  KU812細胞 ,  脱顆粒