Art
J-GLOBAL ID：200902254887284710   Reference number：09A0408061

A SYNTHETIC APPROACH TO DEVELOP PEPTIDE INHIBITORS SELECTIVE FOR BRAIN-TYPE SODIUM CHANNELS ON THE BASIS OF POMPILIDOTOXIN STRUCTURE

ポンピリドトキシン構造に基づく脳型ナトリウムチャンネルに選択的なペプチド阻害薬を開発する合成手法
Author (13)：
YOKOTE Sawana

About YOKOTE Sawana

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
SETOGUCHI Ritsuko

About SETOGUCHI Ritsuko

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
SHIMIZU Eisuke

About SHIMIZU Eisuke

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
MISHIMA Naoki

About MISHIMA Naoki

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
KAWAHARA Kohichi

About KAWAHARA Kohichi

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
KUNIYASU Akihiko

About KUNIYASU Akihiko

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
SHIRASAKI Tetsuya

About SHIRASAKI Tetsuya

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
TAKAHAMA Kazuo

About TAKAHAMA Kazuo

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN

, 
KONNO Katsuhiro

About KONNO Katsuhiro

(Univ. Toyama, Toyama, JPN)

About Univ. Toyama, Toyama, JPN

, 
KAWAI Nobufumi

About KAWAI Nobufumi

(Chiba-Kashiwa Rehabilitation Hospital, Chiba, JPN)

About Chiba-Kashiwa Rehabilitation Hospital, Chiba, JPN

, 
YAMAOKA Kaoru

About YAMAOKA Kaoru

(Hiroshima International Univ., Hiroshima, JPN)

About Hiroshima International Univ., Hiroshima, JPN

, 
KINOSHITA Eiji

About KINOSHITA Eiji

(Hiroshima Univ., Hiroshima, JPN)

About Hiroshima Univ., Hiroshima, JPN

, 
NAKAYAMA Hitoshi

About NAKAYAMA Hitoshi

(Kumamoto Univ., Kumamoto, JPN)

About Kumamoto Univ., Kumamoto, JPN


Material：
Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)

About Heterocycles


Volume： 79  Page： 925-933  Publication year： Apr. 01, 2009 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)
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*vasoactive drug

About vasoactive drug

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*sodium channel blocker

About sodium channel blocker

,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Peptides 
(CF10080G)

About Peptides

,  Basic research of vasoactive drugs and hypotensive drugs 
(GW07040J)

About Basic research of vasoactive drugs and hypotensive drugs

Substance index (10)：
Substance index
Chemical Substance indexed to the Article.
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-D-Arg-Leu-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-D-Arg-Leu-NH2

, 
D-Arg-D-Ile-D-Lys-D-Ile-Gly-D-Leu-D-Phe-D-Asp-D-Gln-D-Leu-D-Ser-D-Arg-D-Leu-NH2

About D-Arg-D-Ile-D-Lys-D-Ile-Gly-D-Leu-D-Phe-D-Asp-D-Gln-D-Leu-D-Ser-D-Arg-D-Leu-NH2

, 
Arg-Ile-Lys-Ile-Gly-D-Leu-D-Phe-D-Asp-D-Gln-D-Leu-D-Ser-D-Arg-D-Leu-NH2

About Arg-Ile-Lys-Ile-Gly-D-Leu-D-Phe-D-Asp-D-Gln-D-Leu-D-Ser-D-Arg-D-Leu-NH2

, 
Arg-Ile-Lys-Ile-Gly-NH2

About Arg-Ile-Lys-Ile-Gly-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-Phe-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-Phe-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-4-Benzoyl-Phe-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-4-Benzoyl-Phe-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-3-(1-Naphthyl)-Ala-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-3-(1-Naphthyl)-Ala-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-3-(2-Naphthyl)-Ala-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-3-(2-Naphthyl)-Ala-NH2

, 
Arg-Ile-Lys-Ile-Gly-Leu-Tyr-NH2

About Arg-Ile-Lys-Ile-Gly-Leu-Tyr-NH2

Reference (18)：
ｍore...
Terms in the title (6)：
Terms in the title
Keywords automatically extracted from the title.
脳

About 脳

, 
ナトリウムチャンネル

About ナトリウムチャンネル

, 
ペプチド

About ペプチド

, 
阻害薬

About 阻害薬

, 
開発

About 開発

, 
手法

About 手法


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