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J-GLOBAL ID：200902256478104835   Reference number：06A0044935

Biosynthesis of 2-Deoxystreptamine by Three Crucial Enzymes in Streptomyces fradiae NBRC 12773

Streptomyces fradiae NBRC 12773における3つの重要酵素による2-デオキシストレプタミンの生合成

Author (5)： KUDO Fumitaka (Tokyo Inst. Technol., Tokyo, JPN) ,  YAMAMOTO Yasuhito (Tokyo Inst. Technol., Tokyo, JPN) ,  YOKOYAMA Kenichi (Tokyo Inst. Technol., Tokyo, JPN) ,  EGUCHI Tadashi (Tokyo Inst. Technol., Tokyo, JPN) ,  KAKINUMA Katsumi (Tokyo Inst. Technol., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 58  Issue： 12  Page： 766-774  Publication year： Dec. 25, 2005 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Streptomyces fradiae ,...
Semi thesaurus term： neo遺伝子

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JST classification (2)： Monosaccharides  (CF10052H) ,  Antibiotic fermentation  (GX03000S)

Substance index (2)： 2-Deoxystreptamine ,  Neomycin B

Reference (33)：

• MAGNET, S. Molecular insights into aminoglycoside action and resistance. Chem Rev. 2005, 105, 477-498
• LAPIDOT, A. Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy. FEBS Lett. 2004, 577, 415-421
• MCPIKE, MP. Specificity of neomycin analogues bound to the packaging region of human immunodeficiency virus type 1 RNA. Bioorg Med Chem. 2004, 12, 1835-1843
• DENAP, JC. Combating drug-resistant bacteria : small molecule mimics of plasmid incompatibility as antiplasmid compounds. J Am Chem Soc. 2004, 126, 15402-15404
• THOMAS, JR. The relationship between aminoglycosides' RNA binding proclivity and their antiplasmid effect on an IncB plasmid. Biochemistry. 2005, 44, 6800-6808

Terms in the title (4)： Streptomyces ,  酵素 ,  2-デオキシストレプタミン ,  生合成