Art

J-GLOBAL ID：200902258266715470   Reference number：06A0455169

Antihypertensive Effect of Angiotensin I-Converting Enzyme Inhibitory Peptides from a Sesame Protein Hydrolysate in Spontaneously Hypertensive Rats

自然発生高血圧ラットにおけるゴマ蛋白質加水分解物由来のアンジオテンシンI変換酵素阻害ペプチドの抗高血圧作用

Author (16)： NAKANO Daisuke (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  OGURA Kyoichi (Inst. for Health Care Sci., Suntory Ltd.) ,  MIYAKOSHI Masazumi (Applied Chemistry Group, Biological & Chemical Res. Dep., Maruzen Pharmaceuticals Co., Ltd.) ,  ISHII Fumie (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  KAWANISHI Hideaki (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  KURUMAZUKA Daisuke (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  KWAK Chol-jun (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  IKEMURA Kenji (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  TAKAOKA Masanori (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences) ,  MORIGUCHI Shigeo (Inst. for Health Care Sci., Suntory Ltd.) ,  IINO Taeko (Inst. for Health Care Sci., Suntory Ltd.) ,  KUSUMOTO Aki (Inst. for Health Care Sci., Suntory Ltd.) ,  ASAMI Sumio (Inst. for Health Care Sci., Suntory Ltd.) ,  SHIBATA Hiroshi (Inst. for Health Care Sci., Suntory Ltd.) ,  KISO Yoshinobu (Inst. for Health Care Sci., Suntory Ltd.) ,  MATSUMURA Yasuo (Dep. of Pharmacology, Osaka Univ. of Pharmaceutical Sciences)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 70  Issue： 5  Page： 1118-1126 (J-STAGE)  Publication year： 2006 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Sesamum indicum ,...
Semi thesaurus term： SHR ,...

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JST classification (2)： Food chemistry,nutritional value  (FJ01020J) ,  Circulation system in general  (EJ04010S)

Reference (27)：

• 1) Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo Jr., J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright Jr., J. T., and Roccella, E. J., National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: JNC 7 report. JAMA, 289, 2560–2572 (2003).
• 2) Yokoyama, K., Chiba, H., and Yoshikawa, M., Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotechnol. Biochem., 56, 1541–1545 (1992).
• 3) Matsufuji, H., Matsui, T., Seki, E., Osajima, K., Nakashima, M., and Osajima, Y., Angiotensin I-converting enzyme inhibitory peptides in an alkaline protease hydrolyzate derived from sardine muscle. Biosci. Biotechnol. Biochem., 58, 2244–2245 (1994).
• 4) Eto, Y., Ito, T., and Nishioka, S., Angiotensin I converting enzyme-inhibitory dipeptides in an alkaline protease hydrolyzate of whey protein. Nippon Eiyou Shokuryo Gakkaisi (in Japanese), 51, 355–359 (1998).
• 5) Kawamura, Y., Angiotensin converting enzyme inhibitory peptides and depressive effect of blood pressure in soy bean protein. Shokuhin Kogyo (in Japanese), 40, 73–82 (1997).

Terms in the title (7)： 自然発生高血圧ラット ,  ゴマ ,  蛋白質加水分解物 ,  アンジオテンシンI ,  酵素阻害 ,  ペプチド ,  高血圧