Art

J-GLOBAL ID：200902258489376120   Reference number：09A0429030

ERK Regulates Renal Cell Proliferation and Renal Cyst Expansion in inv Mutant Mice

ERKはinv変異マウスにおいて腎細胞増殖および腎嚢胞増大を調節する

Author (8)： OKUMURA Yasuko (Dep. of Anatomy and Developmental Biology, Kyoto Prefectural Univ. of Medicine) ,  OKUMURA Yasuko (Dep. of Pediatric Cardiology and Nephrology, Graduate School of Medical Sci., Kyoto Prefectural Univ. of Medicine) ,  SUGIYAMA Noriyuki (Dep. of Anatomy and Developmental Biology, Kyoto Prefectural Univ. of Medicine) ,  TANIMURA Susumu (Dep. of Pharmaceutical Sciences, Graduate School of Biomedical Sciences, Nagasaki Univ.) ,  NISHIDA Masashi (Dep. of Pediatric Cardiology and Nephrology, Graduate School of Medical Sci., Kyoto Prefectural Univ. of Medicine) ,  HAMAOKA Kenji (Dep. of Pediatric Cardiology and Nephrology, Graduate School of Medical Sci., Kyoto Prefectural Univ. of Medicine) ,  KOHNO Michiaki (Dep. of Pharmaceutical Sciences, Graduate School of Biomedical Sciences, Nagasaki Univ.) ,  YOKOYAMA Takahiko (Dep. of Anatomy and Developmental Biology, Kyoto Prefectural Univ. of Medicine)
Material： Acta Histochemica et Cytochemica  (Acta Histochem Cytochem)
Volume： 42  Issue： 2  Page： 39-45 (J-STAGE)  Publication year： 2009 
JST Material Number： Z0149B  ISSN： 0044-5991  CODEN： ACHCBO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cell ,...
Semi thesaurus term： *renal cell ,...

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JST classification (3)： Kidney  (EJ09030X) ,  Cell physiology in general  (EF02010S) ,  Basic medicine on urogenital system  (GM01020T)

Substance index (2)： PD-184352 ,  Bromodeoxyuridine

Reference (25)：

• 1. Bhunia, A. K., Piontek, K., Boletta, A., Liu, L., Qian, F., Xu, P. N., Germino, F. J. and Germino, G. G. (2002) Pkd1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 109; 157-168.
• 2. Bukanov, N. O., Smith, L. A., Klinger, K. W., Ledbetter, S. R. and Ibraghimov-Beskrovnaya, O. (2006) Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine. Nature 444; 949-952.
• 3. Chambard, J. C., Lefloch, R., Pouyssegur, J. and Lenormand, P. (2007) ERK implication in cell cycle regulation. Biochim. Biophys. Acta 1773; 1299-1310.
• 4. Gagnadoux, M. F., Bacri, J. L., Broyer, M. and Habib, R. (1989) Infantile chronic tubulo-interstitial nephritis with cortical microcysts: Variant of nephronophthisis or new disease entity? Pediatr. Nephrol. 3; 50-55.
• 5. Hildebrandt, F., Attanasio, M. and Otto, E. (2009) Nephronophthisis: Disease mechanisms of a ciliopathy. J. Am. Soc. Nephrol. 20; 23-35.

Terms in the title (6)： ERK ,  変異マウス ,  腎細胞 ,  増殖 ,  腎嚢胞 ,  調節