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J-GLOBAL ID：200902262347830182   Reference number：08A0591203

FKBP12.6 disruption impairs glucose-induced insulin secretion

FKBP12.6破壊はグルコース誘導のインシュリン分泌を損傷する

Author (11)： NOGUCHI Naoya (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  YOSHIKAWA Takeo (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  IKEDA Takayuki (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  TAKAHASHI Iwao (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  SHERVANI Nausheen Jamal (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  URUNO Akira (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  YAMAUCHI Akiyo (Dep. of Biochemistry, Nara Medical Univ., Kashihara 634-8521, JPN) ,  NATA Koji (Dep. of Medical Biochemistry, Iwate Medical Univ. School of Pharmacy, Yahaba-cho 028-3603, JPN) ,  TAKASAWA Shin (Dep. of Biochemistry, Nara Medical Univ., Kashihara 634-8521, JPN) ,  OKAMOTO Hiroshi (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  SUGAWARA Akira (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 371  Issue： 4  Page： 735-740  Publication year： Jul. 11, 2008 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： knockout mouse ,  pancreas ,  Islets of Langerhans ,  *internal secretion ,  *cis-trans-isomerase ,  *Membrane Proteins ,  *drug receptor ,  Potassium Channels ,  Endoplasmic Reticulum ,  Calcium ,  ryanodine receptor ,  immunohistochemistry ,  carbohydrate metabolism ,  gene expression ,  Potassium Chloride ,  adenine nucleotide ,  ribonucleotide ,  hexose ,  aldose ,  *insulin secretion ,  *FK506-binding protein 12.6 ,  Insulin-Secreting Cells ,  laboratory animal ,  Mus musculus ,  Ion Transport ,  transportation ,  Biological Transport ,  transmembrane protein ,  ion transport(in vivo) ,  molecular genetic phenomenon
Semi thesaurus term： ATP-sensitive potassium channel ,  *FKBP12.6 ,  beta cell

JST classification (3)： Biological function  (EB03040U) ,  Pancreas  (EJ06050Y) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (4)： adenosine triphosphate ,  Glucose ,  Sulfonylurea ,  cADP ribose

Terms in the title (6)： FKBP12 ,  破壊 ,  グルコース ,  誘導 ,  インシュリン分泌 ,  損傷