Both Insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2<sup>-/-</sup> Mice

SUZUKI R; TOBE K; AOYAMA M; INOUE A; YOSHIMATSU H; MATSUHISA M; NAGASAKA S; OGATA H; TOKUYAMA K

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J-GLOBAL ID：200902267382026746 Reference number：04A0489130

Both Insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2^-/- Mice

Irs2^-/-マウスで,肝臓におけるインシュリンシグナル伝達障害と肥満の両者がインシュリン抵抗性に寄与し,糖尿病を誘発する

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Volume： 279 Issue： 24 Page： 25039-25049 Publication year： Jun. 11, 2004
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Cell physiology in general , Metabolic diseases,nutritional diseases in general.

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Both Insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2-/- Mice

Both Insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2^-/- Mice