Art

J-GLOBAL ID：200902269857802528   Reference number：03A0178705

6-Hydroxyflavonoids as α-Glucosidase Inhibitors from Marjoram (Origanum majorana) Leaves.

マヨラナ(Origanum majorana,シソ科)の葉由来のα-グルコシダーゼ阻害剤としての6-ヒドロキシフラボノイド類

Author (6)： KAWABATA J (Hokkaido Univ., Sapporo, JPN) ,  MIZUHATA K (Hokkaido Univ., Sapporo, JPN) ,  SATO E (Hokkaido Univ., Sapporo, JPN) ,  NISHIOKA T (Hokkaido Univ., Sapporo, JPN) ,  AOYAMA Y (Hokkaido Univ., Sapporo, JPN) ,  KASAI T (Hokkaido Univ., Sapporo, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 67  Issue： 2  Page： 445-447  Publication year： Feb. 23, 2003 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Lamiacea ,...
Semi thesaurus term： glycoside hydrolase ,...

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JST classification (2)： Plant biochemistry  (EH01050J) ,  Enzyme in general  (EB09010D)

Substance index (11)： Sucrose ,  Methanol ,  Baicalein ,  Scutellarein ,  6-Hydroxyluteolin ,  Plantaginin ,  6-Hydroxyluteolin 7-glucoside ,  4′,5,6-Trihydroxy-7-[6-O-[3-(3-methoxy-4-hydroxyphenyl)acryloyl]-β-D-glucopyranosyloxy]flavone ,  3′,4′,5,6-Tetrahydroxy-7-[6-O-[3-(3-methoxy-4-hydroxyphenyl)acryloyl]-β-D-glucopyranosyloxy]flavone ,  Apigenin ,  Luteolin

Reference (12)：

• 1) Puls, W., Keup, U., Krause, H. P., Thomas, G., and Hoffmeister, F., Glucosidase inhibition: a new approach to the treatment of diabetes, obesity, and hyperlipoproteinaemia. Naturwissenschaften, 64, 536-537 (1977).
• 2) Watanabe, J., Kawabata, J., Kurihara, H., and Niki, R., Isolation and identification of α-glucosidase inhibitors from tochu-cha (Eucommia ulmoides). Biosci. Biotechnol. Biochem., 61, 177-178 (1997).
• 3) Kurihara, H., Ando, J., Hatano, M., and Kawabata, J., Sulfoquinovosyldiacylglycerol as an α-glucosidase inhibitor. Bioorg. Med. Chem. Lett., 61, 263-266 (1997).
• 4) Nishioka, T., Watanabe, J., Kawabata, J., and Niki, R., Isolation and activity of N-p-coumaroyltyramine, an α-glucosidase inhibitor in welsh onion (Allium fistulosum). Biosci. Biotechnol. Biochem., 61, 1138-1141 (1997).
• 5) Nishioka, T., Kawabata, J., and Aoyama, Y., Baicalein, an α-glucosidase inhibitor from Scutellaria baicalensis. J. Nat. Prod., 61, 1413-1415 (1998).

Terms in the title (6)： マヨラナ ,  Origanum ,  Majorana ,  シソ科 ,  葉 ,  α-グルコシダーゼ阻害剤