Art

J-GLOBAL ID：200902271143962070   Reference number：09A0946921

A phase II, open-label, sequential-cohort, dose-escalation study of romiplostim in Japanese patients with chronic immune thrombocytopenic purpura

慢性免疫性血小板減少性紫斑病の日本人患者におけるロミプロスチムの第二相オープンラベル連続コホート用量増加試験

Author (9)： SHIRASUGI Yukari (Tokai Univ. Hospital, Isehara, JPN) ,  ANDO Kiyoshi (Tokai Univ. Hospital, Isehara, JPN) ,  HASHINO Satoshi (Hokkaido Univ. Hospital, Sapporo, JPN) ,  NAGASAWA Toshiro (Tsukuba Univ. Hospital, Tsukuba, JPN) ,  KURATA Yoshiyuki (Osaka Univ. Hospital, Suita, JPN) ,  KISHIMOTO Yuji (Kansai Medical Univ. Takii Hospital, Moriguchi, JPN) ,  IWATO Koji (Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima, JPN) ,  OHTSU Tomoko (Amgen KK, Tokyo, JPN) ,  BERGER Dietmar P. (Amgen Inc., CA, USA)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 90  Issue： 2  Page： 157-165  Publication year： Sep. 2009 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *thrombopenic purpura ,...
Semi thesaurus term： Platelet Count ,...

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JST classification (2)： Clinical application of drugs acting on blood and body fluid  (GW14020X) ,  Drug therapy(=pharmacotherapy)for hematologic diseases in general  (GK05020P)

Reference (23)：

• British Committee for Standards in Haematology General Hematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol. 2003, 120, 574-596
• CINES, DB. Immune thrombocytopenic purpura. N Engl J Med. 2002, 346, 995-1008
• GEORGE, JN. Idiopathic thrombocytopenic purpura : a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996, 88, 3-40
• MCMILLAN, R. The pathogenesis of chronic immune thrombocytopenic purpura. Semin Hematol. 2007, 44, S3-S11
• BROMBERG, ME. Immune thrombocytopenic purpura : the changing therapeutic landscape. N Engl J Med. 2006, 355, 1643-1645

Terms in the title (10)： 慢性 ,  免疫性血小板減少性紫斑病 ,  日本人 ,  患者 ,  ロミプロスチム ,  第二相 ,  ラベル ,  コホート ,  用量 ,  試験