Art

J-GLOBAL ID：200902271483349527   Reference number：08A0939203

Evaluation of Adjuvant Activities Using Human Antigen Presenting Cells in Vitro

ヒト抗原提示細胞を用いたアジュバント活性のin Vitro評価

Author (8)： HIGASHI Takehiro (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.) ,  WAKUI Masatoshi (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.) ,  NAKANO Kazuhisa (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.) ,  NAKANO Kazuhisa (The First Dep. of Internal Medicine, Univ. of Occupational and Environmental Health) ,  HASHIMOTO Kumiko (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.) ,  TAKAGI Rie (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.) ,  TANAKA Yoshiya (The First Dep. of Internal Medicine, Univ. of Occupational and Environmental Health) ,  MATSUSHITA Sho (Dep. of Allergy and Immunology, Fac. of Medicine, Saitama Medical Univ.)
Material： Allergology International  (Allergol Int)
Volume： 57  Issue： 3  Page： 219-222 (J-STAGE)  Publication year： 2008 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...

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JST classification (2)： Clinical therapeutics  (GC03013R) ,  Treatment for immunologic diseases,allergic diseases.  (GD04030Y)

Substance index (2)： cAMP ,  Forskolin

Reference (8)：

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• 2. Kalinski P, Schuitemaker JH, Hilkens CM, Kapsenberg ML. Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J Immunol 1998; 161: 2804-2809.
• 3. Zidek Z. Adenosine-cyclic AMP pathways and cytokine expression. Eur Cytokine Netw 1999; 10: 319-328.
• 4. Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 1999; 284: 770-776.
• 5. Wakui M, Nakano K, Matsushita S. Notch ligand mRNA levels of human APCs predict Th1/Th2-promoting activities. Biochem Biophys Res Commun 2007; 358: 596-601.

Terms in the title (5)： ヒト ,  抗原提示細胞 ,  アジュバント ,  活性 ,  評価