Art

J-GLOBAL ID：200902271927383026   Reference number：09A0389999

Pathogen recognition by innate immunity and its signaling

先天的免疫による病原体認識とその信号化

Author (1)： AKIRA Shizuo (Lab. of Host Defense, WPI Immunology Frontier Res. Center, Osaka Univ.)
Material： Proceedings of the Japan Academy. Series B. Physical and Biological Sciences  (日本学士院紀要 B)
Volume： 85  Issue： 4  Page： 143-156 (J-STAGE)  Publication year： 2009 
JST Material Number： G0485B  ISSN： 0386-2208  CODEN： PJABDW  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *natural immunity ,...
Semi thesaurus term： TLR ,...

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JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (56)：

• 1) Akira, S., Uematsu, S. and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 24, 783–801.
• 2) Akira, S., Isshiki, H., Sugita, T., Tanabe, O., Kinoshita, S., Nishio, Y. et al. (1990) A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9, 1897–1906.
• 3) Akira, S., Nishio, Y., Inoue, M., Wang, X., Wei, S., Matsuzaka, T. et al. (1994) Molecular cloning of APRF, a novel ISGF3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77, 63–71.
• 4) Minami, M., Inoue, M., Wei, S., Takeda, K., Matsumoto, M., Kishimoto, T. et al. (1996) STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line. Proc. Natl. Acad. Sci., USA 93, 3963–3966.
• 5) Muzio, M., Ni, J., Feng, P. and Dixit, V.M. (1997) IRAK(Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278, 1612–1615.

Terms in the title (2)： 先天的免疫 ,  病原体