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J-GLOBAL ID：200902277102933404   Reference number：03A0735583

Concise Synthesis and Biological Activities of 2α-Alkyl- and 2α-(ω-Hydroxyalkyl)-20-epi-1α,25-dihydroxyvitamin D₃.

2α-アルキル-及び2α-(ω-ヒドロキシアルキル)-20-epi-1α,25-ジヒドロキシビタミンD₃の簡潔合成及び生物活性

Author (9)： HONZAWA S (Teikyo Univ., Kanagawa, JPN) ,  SUHARA Y (Teikyo Univ., Kanagawa, JPN) ,  NIHEI K (Teikyo Univ., Kanagawa, JPN) ,  KISHIMOTO S (Teikyo Univ., Kanagawa, JPN) ,  KURIHARA M (National Inst. Health Sci., Tokyo, JPN) ,  SUGIURA T (Teikyo Univ., Kanagawa, JPN) ,  WAKU K (Teikyo Univ., Kanagawa, JPN) ,  TAKAYAMA H (Teikyo Univ., Kanagawa, JPN) ,  KITTAKA A (Teikyo Univ., Kanagawa, JPN)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 13  Issue： 20  Page： 3503-3506  Publication year： Oct. 20, 2003 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *secosteroid ,...

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JST classification (2)： Steroids  (CF10040O) ,  Vitamin D  (EB07050H)

Substance index (16)： (S)-2-Methyl-6-[4-(bromomethylene)-7aβ-methylhydrindane-1β-yl]heptane-2-ol ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-ethyl-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-propyl-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-butyl-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-(tert-butyldimethylsiloxymethyl)-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-[2-(tert-butyldimethylsiloxy)ethyl]-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-[3-(tert-butyldimethylsiloxy)propyl]-1-octene-7-yne ,  (3R,4S,5R)-3,5-Bis(tert-butyldimethylsiloxy)-4-[4-(tert-butyldimethylsiloxy)butyl]-1-octene-7-yne ,  Methyl 2,3-anhydro-4-O,6-O-[(R)-benzylidene]-α-D-mannopyranoside ,  (20S)-1α,25-Dihydroxy-2α-ethylcholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-propylcholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-butylcholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-(hydroxymethyl)cholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-(2-hydroxyethyl)cholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-(3-hydroxypropyl)cholecalciferol ,  (20S)-1α,25-Dihydroxy-2α-(4-hydroxybutyl)cholecalciferol

Terms in the title (4)： ヒドロキシアルキル ,  EPI ,  ジヒドロキシビタミンD3 ,  生物活性