Art

J-GLOBAL ID：200902277808033538   Reference number：03A0181826

Leptin Causes Nitric-Oxide Independent Coronary Artery Vasodilation in Humans.

レプチンはヒトにおいて酸化窒素非依存性の冠状動脈血管拡張を起こす

Author (6)： MATSUDA K (Hiroshima Univ., Hiroshima, JPN) ,  TERAGAWA H (Hiroshima Univ., Hiroshima, JPN) ,  FUKUDA Y (Hiroshima Univ., Hiroshima, JPN) ,  NAKAGAWA K (Hiroshima Univ., Hiroshima, JPN) ,  HIGASHI Y (Hiroshima Univ., Hiroshima, JPN) ,  CHAYAMA K (Hiroshima Univ., Hiroshima, JPN)
Material： Hypertension Research  (Hypertens Res)
Volume： 26  Issue： 2  Page： 147-152  Publication year： Feb. 2003 
JST Material Number： Y0303A  ISSN： 0916-9636  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： vasodilator action ,...
Semi thesaurus term： *coronary artery ,...

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JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： L-NMMA

Reference (25)：

• 1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432.
• 2. Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
• 3. Ogawa Y, Masuzaki H, Isse N, et al: Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J Clin Invest 1995; 96: 1647-1652.
• 4. Aizawa-Abe M, Ogawa Y, Masuzaki H, et al: Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 2000; 105: 1243-1252.
• 5. Shek EW, Brands MW, Hall JE: Chronic leptin infusion increases arterial pressure. Hypertension 1998; 31: 409-414.

Terms in the title (6)： レプチン ,  ヒト ,  酸化窒素 ,  非依存性 ,  冠状動脈 ,  血管拡張