Art

J-GLOBAL ID：200902278040095934   Reference number：09A0205809

Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation

タウ蛋白質のSer214におけるリン酸化は14-3-3蛋白質との相互作用を仲介する:タウ凝集の機構の意味合い

Author (7)： SADIK Golam (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  TANAKA Toshihisa (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  KATO Kiyoko (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  YAMAMORI Hidenaga (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  NESSA Begum Nurun (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  MORIHARA Takashi (Osaka Univ. Graduate School of Medicine, Osaka, JPN) ,  TAKEDA Masatoshi (Osaka Univ. Graduate School of Medicine, Osaka, JPN)
Material： Journal of Neurochemistry  (J Neurochem)
Volume： 108  Issue： 1  Page： 33-43  Publication year： Jan. 2009 
JST Material Number： B0504B  ISSN： 0022-3042  CODEN： JONRA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *adaptor protein ,  *tau protein ,  phosphorylation ,  intermolecular interaction ,  aggregation ,  microtubule-associated protein ,  *Alzheimer Disease ,  Dementia ,  protein kinase A ,  serine-threonine kinase ,  binding site ,  immunoprecipitation ,  Western blotting ,  plasma resonance ,  electron microscopy ,  Polymerization ,  site-directed mutagenesis ,  *14-3-3 Proteins ,  protein aggregation ,  Neurofibrillary Tangle ,  Akt/protein kinase B ,  protein-protein interaction ,  Surface Plasmon Resonance ,  bioassay ,  immunoassay
Semi thesaurus term： neurofibrillary tangle ,  protein kinase B ,  protein interaction ,  surface plasmon resonance

JST classification (2)： Biological function  (EB03040U) ,  Basic neurology  (GN01020W)

Terms in the title (6)： タウ蛋白質 ,  リン酸化 ,  14-3-3蛋白質 ,  相互作用 ,  仲介 ,  凝集