Art

J-GLOBAL ID：200902278672570263   Reference number：04A0543165

Regioselective Monosulfation and Disulfation of the Phytoestrogens Daidzein and Genistein by Human Liver Sulfotransferases

ヒト肝臓硫黄トランスフェラーゼによる植物エストロゲン,ダイゼインとゲニステインの領域選択的単硫酸化と二硫酸化

Author (9)： NAKANO H (Japan Tobacco Inc., Tokyo, JPN) ,  OGURA K (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  TAKAHASHI E (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  HARADA T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  NISHIYAMA T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  MURO K (National Cancer Center Hospital, Tokyo, JPN) ,  HIRATSUKA A (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  KADOTA S (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  WATABE T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN)
Material： Drug Metabolism and Pharmacokinetics  (Drug Metab Pharmacokinet)
Volume： 19  Issue： 3  Page： 216-226  Publication year： Jun. 30, 2004 
JST Material Number： X0758A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *phytohormone ,...
Semi thesaurus term： 植物エストロゲン

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=04A0543165&from=J-GLOBAL&jstjournalNo=X0758A") }}

JST classification (2)： Enzyme in general  (EB09010D) ,  Basic biopharmacy  (GY01021U)

Substance index (2)： Daidzein ,  Genistein

Reference (35)：

• 1) Pereira, M. A., Barnes, L. H., Rassman, V. L., Kelloff, G. V. and Steele, V. E.: Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents. Carcinogenesis, 15: 1049-1054 (1994).
• 2) Barnes, S.: The chemopreventive properties of soy isoflavonoids in animal models of breast cancer. Breast Cancer Res. Treat., 46: 169-179 (1997).
• 3) Peterson, G. and Barnes, S.: Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem. Biophys. Res. Commun., 179: 661-667 (1991).
• 4) Peterson, G. and Barnes, S.: Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor tyrosine autophosphorylation. Prostate, 22: 335-345 (1993).
• 5) Ingram, D., Sanders, K., Kolybaba, M. and Lopez, D.: Case-control study of phyto-estrogens and breast cancer. Lancet, 350: 990-994 (1997).

Terms in the title (7)： ヒト ,  肝臓 ,  硫黄トランスフェラーゼ ,  植物エストロゲン ,  ダイゼイン ,  ゲニステイン ,  硫酸化