Art

J-GLOBAL ID：200902280119635777   Reference number：07A0185575

Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma

小児急性リンパ芽球白血病と悪性リンパ腫におけるメトトレキセート有害事象および排泄と関係する遺伝的多型性

Author (12)： IMANISHI Hiroyuki (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  OKAMURA Noboru (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  YAGI Mariko (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  NORO Yukari (Kobe Univ., Kobe, JPN) ,  MORIYA Yuka (Kobe Univ., Kobe, JPN) ,  NAKAMURA Tsutomu (Kobe Univ., Kobe, JPN) ,  HAYAKAWA Akira (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  TAKESHIMA Yasuhiro (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  SAKAEDA Toshiyuki (Kobe Univ., Kobe, JPN) ,  MATSUO Masafumi (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  OKUMURA Katsuhiko (Kobe Univ. Graduate School of Medicine, Kobe, JPN) ,  OKUMURA Katsuhiko (Kobe Univ., Kobe, JPN)
Material： Journal of Human Genetics  (J Hum Genet)
Volume： 52  Issue： 2  Page： 166-171  Publication year： 2007 
JST Material Number： Z0756A  ISSN： 1434-5161  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Polymorphism, Genetic ,...

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JST classification (3)： Structure and chemistry of genes  (EC02020U) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： Methotrexate

Reference (25)：

• ABBOTT, BL. ABCG2 (BCRP) expression in normal and malignant hematopoietic cells. Hematol Oncol. 2003, 21, 115-130
• ADLER, V. Regulation of JNK signaling by GSTp. EMBO J. 1999, 18, 1321-1334
• ANDERSON, JR. Long-term follow-up of patients treated with COMP or LSA2L2 therapy for childhood non-Hodgkin's lymphoma : a report of CCG-551 from the Children's Cancer Group. J Clin Oncol. 1993, 11, 1024-1032
• APLENC, R. Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia. Br J Haematol. 2004, 125, 421-434
• CHIUSOLO, P. Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate. Ann Oncol. 2002, 13, 1915-1918

Terms in the title (6)： 小児急性リンパ芽球白血病 ,  悪性リンパ腫 ,  メトトレキセート ,  有害事象 ,  排泄 ,  遺伝的多型性