Art

J-GLOBAL ID：200902281054697695   Reference number：09A0291279

Effects of Acetate on Lipid Metabolism in Muscles and Adipose Tissues of Type 2 Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) Rats

2型糖尿病のOtsuka Long-Evans Tokushima Fatty(OLETF)ラットの筋肉および脂肪組織における脂質代謝に対する酢酸塩の影響

Author (12)： YAMASHITA Hiromi (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  MARUTA Hitomi (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  JOZUKA Michiyo (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  KIMURA Rie (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  IWABUCHI Hiromi (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  YAMATO Makiko (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  SAITO Tsukasa (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  FUJISAWA Katsuhiko (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  TAKAHASHI Yoshitaka (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  KIMOTO Masumi (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  HIEMORI Miki (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.) ,  TSUJI Hideaki (Dep. of Nutritional Sci., Fac. of Health and Welfare Sci., Okayama Prefectural Univ.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 73  Issue： 3  Page： 570-576 (J-STAGE)  Publication year： 2009 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Adipose Tissue ,...
Semi thesaurus term： oxygen consumption ,...

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JST classification (1)： Basic research of drugs acting on lipid metabolism  (GW13040M)

Reference (43)：

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• 2) Roden, M., Price, T. B., Perseghin, G., Petersen, K. F., Rothman, D. L., Cline, G. W., and Shulman, G. I., Mechanism of free fatty acid-induced insulin resistance in humans. J. Clin. Invest., 97, 2859–2865 (1996).
• 3) Magnan, C., Gilbert, M., and Kahn, B. B., Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle. Lipids, 31, 1141–1149 (1996).
• 4) Dresner, A., Laurent, D., Marcucci, M., Griffin, M. E., Dufour, S., Cline, G. W., Slezak, L. A., Andersen, D. K., Hundal, R. S., Rothman, D. L., Petersen, K. F., and Shulman, G. I., Effect of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest., 103, 253–259 (1999).
• 5) Yamashita, H., Fujisawa, K., Ito, E., Idei, S., Kawaguchi, N., Kimoto, M., Hiemori, M., and Tsuji, H., Improvement of obesity and glucose tolerance by acetate in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Biosci. Biotechnol. Biochem., 71, 1236–1243 (2007).

Terms in the title (6)： 2型糖尿病 ,  ラット ,  筋肉 ,  脂肪組織 ,  脂質代謝 ,  酢酸塩