Art

J-GLOBAL ID：200902281870891203   Reference number：06A0492741

Heterotrimeric G Protein Gα₁₃-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts

心線維芽細胞の2つの異なる経路を通したヘテロ三量体G蛋白質Gα₁₃によるサイトカインmRNAの誘導

Author (8)： NAGAMATSU Yuichi (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN) ,  NISHIDA Motohiro (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN) ,  ONOHARA Naoya (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN) ,  FUKUTOMI Masashi (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN) ,  MARUYAMA Yoshiko (Lab. of Cellular Signaling, Graduate School of Pharmaceutical Sciences, Univ. of Tokyo, JPN) ,  KOBAYASHI Hiroyuki (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN) ,  SATO Yoji (National Inst. of Health Sciences, JPN) ,  KUROSE Hitoshi (Dep. of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 101  Issue： 2  Page： 144-150 (J-STAGE)  Publication year： 2006 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： rat ,...
Semi thesaurus term： *G protein ,...

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JST classification (3)： Heart  (EJ04020D) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Substance index (5)： ST-1943 ,  Carbazole ,  BAPTA-AM ,  Y-27632 ,  SKF-96365

Reference (24)：

• 1 Brown RD, Ambler SK, Mitchell MD, Long CS. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol. 2005;45:657–687.
• 2 Manabe I, Shindo T, Nagai R. Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy. Circ Res. 2002;91:1103–1113.
• 3 Siwik DA, Colucci WS. Regulation of matrix metalloproteinases by cytokines and reactive oxygen/nitrogen species in the myocardium. Heart Fail Rev. 2004;9:43–51.
• 4 Murray DR, Prabhu SD, Chandrasekar B. Chronic β-adrenergic stimulation induces myocardial proinflammatory cytokine expression. Circulation 2000;101:2338–2341.
• 5 Jaffre F, Callebert J, Sarre A, Etienne N, Nebigil CG, Launay JM, et al. Involvement of the serotonin 5-HT_2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts. Circulation. 2004;110:969–974.

Terms in the title (8)： 心 ,  線維芽細胞 ,  経路 ,  ヘテロ三量体G蛋白質 ,  Gα13 ,  サイトカイン ,  mRNA ,  誘導