Art
J-GLOBAL ID：200902285849322709   Reference number：09A0009447

Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer

RhoAの高発現は腫瘍播種を促進する:ロバスタチンでRhoAを抑制することは卵巣癌に有効であるかもしれない
Author (7)：
HORIUCHI Akiko

About HORIUCHI Akiko

(Shinshu Univ. School of Medicine, Matsumoto)

About Shinshu Univ. School of Medicine, Matsumoto

, 
KIKUCHI Norihiko

About KIKUCHI Norihiko

(Shinshu Univ. School of Medicine, Matsumoto)

About Shinshu Univ. School of Medicine, Matsumoto

, 
OSADA Ryosuke

About OSADA Ryosuke

(Shinshu Univ. School of Medicine, Matsumoto)

About Shinshu Univ. School of Medicine, Matsumoto

, 
WANG Cuiju

About WANG Cuiju

(Shinshu Univ. School of Medicine, Matsumoto)

About Shinshu Univ. School of Medicine, Matsumoto

, 
HAYASHI Akiko

About HAYASHI Akiko

(Shinshu Univ. School of Medicine, Matsumoto)

About Shinshu Univ. School of Medicine, Matsumoto

, 
NIKAIDO Toshio

About NIKAIDO Toshio

(Toyama Univ., Fac. of Medicine, Toyama)

About Toyama Univ., Fac. of Medicine, Toyama

, 
KONISHI Ikuo

About KONISHI Ikuo

(Kyoto Univ. Graduate School of Medicine, Kyoto, JPN)

About Kyoto Univ. Graduate School of Medicine, Kyoto, JPN


Material：
Cancer Science  (Cancer Sci)

About Cancer Science


Volume： 99  Issue： 12  Page： 2532-2539  Publication year： Dec. 2008 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)
Thesaurus term：
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Rho protein

About Rho protein

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
cellular signal transduction

About cellular signal transduction

,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Basic research of antitumor(=antineoplastic)drugs 
(GW16010A)

About Basic research of antitumor(=antineoplastic)drugs

,  Experimental treatment for tumors 
(GE02040Y)

About Experimental treatment for tumors

Substance index (2)：
Substance index
Chemical Substance indexed to the Article.
Lovastatin

About Lovastatin

, 
Pravastatin

About Pravastatin

Reference (35)：
  • OZOLS, RF. Epithelial ovarian cancer. Principles and Practice of Gynecologic Oncology. 2000, 981-1057
  • MUTCH, DG. Biology of epithelial ovarian cancer. Clin Obstet Gynecol. 1994, 37, 406-422
  • IMAI, T. Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol. 2003, 163, 1437-1447
  • GAROFALO, A. The combination of the tyrosine kinase receptor inhibitor SU6668 with paclitaxel affects ascites formation and tumor spread in ovarian carcinoma xenografts growing orthotopically. Clin Cancer Res. 2003, 9, 3476-3485
  • XU, Y. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients. Clin Cancer Res. 1995, 1, 1223-1232
ｍore...
Terms in the title (6)：
Terms in the title
Keywords automatically extracted from the title.
RhoA

About RhoA

, 
発現

About 発現

, 
腫瘍播種

About 腫瘍播種

, 
促進

About 促進

, 
ロバスタチン

About ロバスタチン

, 
卵巣癌

About 卵巣癌


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