Art

J-GLOBAL ID：200902286011049195   Reference number：05A0354022

Molecular mechanism for production of reactive oxygen species by neutrophils

好中球による活性酸素生成の分子メカニズム

Author (3)： MIYANO KEI (九大 生体防御医研) ,  TAMURA MINORU (愛媛大 工) ,  SUMIMOTO HIDEKI (九大 生体防御医研)
Material： 炎症・再生  (Inflammation and Regeneration)
Volume： 25  Issue： 2  Page： 113-117  Publication year： Mar. 25, 2005 
JST Material Number： Y0899A  ISSN： 1346-8022  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *Neutrophils ,...
Semi thesaurus term： NADH oxidoreductase ,...

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JST classification (1)： Biophylaxis and immune systems in general  (ED01010F)

Reference (20)：

• 1) Vignais PV: The superoxide-generating NADPH oxidase. CMLS, 59: 1428-1459, 2002.
• 2) 住本英樹 : 活性酸素による自然免疫病原体排除機構. 細胞工学, 21: 1312-1317, 2002.
• 3) Shiose A, Sumimoto H: Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase. J Biol Chem, 275: 13793-13801.
• 4) Ago T, Nunoi H, Ito T, Sumimoto H: Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47^phox. J Biol Chem, 274: 33644-33653, 1999.
• 5) Ago T, Kuribayashi F, Hiroaki H, Takeya R, Ito T, Kohda D, Sumimoto H: Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation. Proc Natl Acad Sci USA, 100: 4474-4479, 2003.

Terms in the title (3)： 好中球 ,  活性酸素生成 ,  分子メカニズム