Art

J-GLOBAL ID：200902286575536703   Reference number：05A0381892

Construction of Human Fab Library and Isolation of Monoclonal Fabs with Rabies Virus-Neutralizing Ability

狂犬病ウイルス中和抗体を用いたヒトFabライブラリーの構築とモノクローナルFabの単離

Author (5)： ANDO Tadasuke (Oita Univ., Oita, JPN) ,  YAMASHIRO Tetsu (Oita Univ., Oita, JPN) ,  TAKITA-SONODA Yoshiko (Oita Univ., Oita, JPN) ,  MANNEN Kazuaki (Oita Univ., Oita, JPN) ,  NISHIZONO Akira (Oita Univ., Oita, JPN)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 49  Issue： 4  Page： 311-322  Publication year： Apr. 20, 2005 
JST Material Number： F0715A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： peptide library ,...
Semi thesaurus term： Fab fragment ,...

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JST classification (2)： Antigens,antibodies,complements in general  (ED04010A) ,  Virology in general  (EG04010J)

Reference (31)：

• ANDRIS-WIDHOPF, J. Generation of antibody libraries : PCR amplification and assembly of light- and heavy-chain coding sequences. Phage display : a laboratory manual. 2001, 9.1-9.113
• BREKKE, O. H. New technologies in therapeutic antibody development. Curr. Opin. Pharmacol. 2003, 3, 544-550
• BURIONI, R. Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 355-359
• BURTON, D. R. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science. 1994, 266, 1024-1027
• CARDOSO, D. F. Neutralizing human anti crotoxin scFv isolated from a nonimmunized phage library. Scand. J. Immunol. 2000, 51, 337-344

Terms in the title (6)： 狂犬病ウイルス ,  中和抗体 ,  ヒト ,  ライブラリー ,  構築 ,  単離