Art

J-GLOBAL ID：200902289566377138   Reference number：07A0369002

Analysis of p53 and K-Ras Gene Mutations in Patients with Chronic Bronchitis Using Laser Capture Microdissection Microscope and Mutation Detection

レーザキャプチャマイクロディセクション顕微鏡及び突然変異検出法を用いた慢性気管支炎患者におけるp53及びK-Ras遺伝子変異の解析

Author (6)： ZHENG Kui-Cheng (Univ. Ryukyus) ,  ZHENG Kui-Cheng (Public Health, Univ. Pittsburgh) ,  TODORIKI Hidemi (Univ. Ryukyus) ,  KATSUMATA Yuriko (Univ. Ryukyus) ,  GAO Wei-Min (Public Health, Univ. Pittsburgh) ,  KEOHAVONG Phouthone (Public Health, Univ. Pittsburgh)
Material： 人間ドック
Volume： 21  Issue： 6  Page： 19-21  Publication year： Mar. 2007 
JST Material Number： L0494A  ISSN： 1880-1021  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Bronchitis ,...
Semi thesaurus term： Bronchitis, Chronic ,...

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JST classification (2)： Respiratory system diagnosis  (GI02000S) ,  Genetic variation  (EC01030Y)

Reference (16)：

• SUZUKI, Y. Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene. 1990, 5, 1037-1043
• SUGIO, K. ras gene mutation as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res. 1992, 52, 2903-2906
• RODENHUIS, S. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res. 1992, 52, 2665s-2669s
• HOLLSTEIN, M. p53 mutations in human cancers. Science. 1991, 253, 49-53
• GREENBLATT, MS. Mutations in the p53 tumor suppressor gene : clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994, 54, 4855-4878

Terms in the title (9)： レーザキャプチャマイクロディセクション ,  顕微鏡 ,  突然変異検出 ,  慢性気管支炎 ,  患者 ,  p53 ,  k-ras遺伝子 ,  変異 ,  解析