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J-GLOBAL ID：200902289981412798   Reference number：07A0609704

Computational Characterization of Structural Role of the Non-active Site Mutation M36I of Human Immunodeficiency Virus Type 1 Protease

ヒト免疫不全ウイルス1型プロテアーゼの非活性部位変異M36Iの構造的役割のコンピュータによる特性化

Author (8)： ODE Hirotaka (Graduate School of Pharmaceutical Sciences, Chiba Univ., 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, JPN) ,  MATSUYAMA Shou (Graduate School of Pharmaceutical Sciences, Chiba Univ., 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, JPN) ,  HATA Masayuki (Graduate School of Pharmaceutical Sciences, Chiba Univ., 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, JPN) ,  NEYA Saburo (Graduate School of Pharmaceutical Sciences, Chiba Univ., 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, JPN) ,  KAKIZAWA Junko (AIDS Res. Center, National Inst. of Infectious Diseases, 4-7-1 Gakuen, Musashimurayama, Tokyo 208-1011, JPN) ,  SUGIURA Wataru (AIDS Res. Center, National Inst. of Infectious Diseases, 4-7-1 Gakuen, Musashimurayama, Tokyo 208-1011, JPN) ,  HOSHINO Tyuji (Graduate School of Pharmaceutical Sciences, Chiba Univ., 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, JPN) ,  HOSHINO Tyuji (PRESTO, JST, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, JPN)
Material： Journal of Molecular Biology  (J Mol Biol)
Volume： 370  Issue： 3  Page： 598-607  Publication year： Jul. 13, 2007 
JST Material Number： D0124B  ISSN： 0022-2836  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： HIV1 ,...
Semi thesaurus term： *HIV protease

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JST classification (2)： Enzyme in general  (EB09010D) ,  Virus biochemistry  (EG04030F)

Substance index (1)： Nelfinavir

Terms in the title (7)： ヒト免疫不全ウイルス1型 ,  プロテアーゼ ,  活性部位 ,  変異 ,  役割 ,  コンピュータ ,  特性化