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J-GLOBAL ID：200902291031811470   Reference number：07A0998642

Facilitated activation of metabotropic glutamate receptors in cerebellar Purkinje cells in glutamate transporter EAAT4-deficient mice

グルタミン酸輸送体EAAT4欠損マウスの小脳Purkinje細胞における向代謝性グルタミン酸受容体の促進性活性化

Author (8)： NIKKUNI Osamu (Dep. of Neurophysiology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  NIKKUNI Osamu (Dep. of Otolaryngology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  TAKAYASU Yukihiro (Dep. of Neurophysiology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  TAKAYASU Yukihiro (Dep. of Otolaryngology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  IINO Masae (Dep. of Neurophysiology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  TANAKA Kohichi (Lab. of Molecular Neuroscience, School of Biomedical Sci. and Medical Res. Inst., Tokyo Medical and Dental Univ. ...) ,  OZAWA Seiji (Dep. of Neurophysiology, Gunma Univ. Graduate School of Medicine, Showa-machi, Maebashi, Gunma 371-8511, JPN) ,  OZAWA Seiji (Regent Office, Gunma Univ., Aramaki, Maebashi, Gunma 371-8510, JPN)
Material： Neuroscience Research  (神経科学)
Volume： 59  Issue： 3  Page： 296-303  Publication year： Nov. 2007 
JST Material Number： D0210C  ISSN： 0168-0102  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Purkinje Cells ,...
Semi thesaurus term： EAAC1 protein ,...

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JST classification (2)： Central nervous system  (EJ12030F) ,  Receptors on cell membrane  (EF04030C)

Substance index (2)： DL-TBOA ,  NBQX

Reference (36)：

• Auger, C., Attwell, D., 2000. Fast removal of synaptic glutamate by post-synaptic transporters. Neuron 28, 548-557.
• Batchelor, A.M., Garthwaite, J., 1997. Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway. Nature 385, 74-77.
• Baude, A., Nusser, Z., Roberts, J.D., Mulvihill, E., McIlhinney, R.A., Somogyi, P., 1993. The metabotropic glutamate receptor (mGluR1a) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11, 771-787.
• Brasnjo, G., Otis, T.S., 2001. Neuronal glutamate transporters control activation of postsynaptic metabotropic glutamate receptors and influence cerebellar long-term depression. Neuron 31, 607-616.
• Brasnjo, G., Otis, T.S., 2004. Isolation of glutamate transport-coupled charge flux and estimation of glutamate uptake at the climbimg fiber-Purkinje cell synapse. Proc. Natl. Acad. Sci. U.S.A. 101, 6273-6278.

Terms in the title (7)： グルタミン酸輸送体 ,  EAAT4 ,  欠損 ,  マウス ,  小脳Purkinje細胞 ,  向代謝性グルタミン酸受容体 ,  活性化