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J-GLOBAL ID：200902294797737521   Reference number：08A0729200

Synthesis of Rubrivivax gelatinosus Lipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities

免疫賦活活性および阻害活性の構造基盤の研究のためのRubrivivax gelatinosusリピドAおよび類似体の合成

Author (7)： FUKASE Yoshiyuki (Dep. of Chemistry, Graduate School of Sci., Osaka Univ.) ,  FUJIMOTO Yukari (Dep. of Chemistry, Graduate School of Sci., Osaka Univ.) ,  ADACHI Yo (Dep. of Chemistry, Graduate School of Sci., Osaka Univ.) ,  SUDA Yasuo (Dep. of Nanostructure and Advanced Materials, Graduate School of Sci. and Engineering, Kagoshima Univ.) ,  KUSUMOTO Shoichi (Dep. of Chemistry, Graduate School of Sci., Osaka Univ.) ,  KUSUMOTO Shoichi (Suntory Inst. for Bioorganic Res.) ,  FUKASE Koichi (Dep. of Chemistry, Graduate School of Sci., Osaka Univ.)
Material： Bulletin of the Chemical Society of Japan  (Bull Chem Soc Jpn)
Volume： 81  Issue： 7  Page： 796-819 (J-STAGE)  Publication year： 2008 
JST Material Number： G0450A  ISSN： 0009-2673  CODEN： BCSJA8  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Structure-Activity Relationship ,...
Semi thesaurus term： endotoxin

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JST classification (3)： Polysaccharides  (CF10054P) ,  Carbohydrates and sugar chains in general  (EB06010I) ,  Biophylaxis and immune systems in general  (ED01010F)

Reference (72)：

• 1) S. Akira, S. Uematsu, O. Takeuchi, Cell 2006, 124, 783.
• 2) E. Meylan, J. Tschopp, M. Karin, Nature 2006, 442, 39.
• 3) J. H. Fritz, S. E. Girardin, J. Endotoxin Res. 2005, 11, 390.
• 4) B. Pulendran, K. Palucka, J. Banchereau, Science 2001, 293, 253.
• 5) A. Aderem, R. J. Ulevitch, Nature 2000, 406, 782.

Terms in the title (6)： 免疫賦活活性 ,  阻害活性 ,  基盤 ,  研究 ,  リピドA ,  類似体