Art

J-GLOBAL ID：200902296519779550   Reference number：08A1162334

Three-dimensional Reconstruction of Human Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Revealed an Ellipsoidal Structure with Orifices beneath the Putative Transmembrane Domain

ヒト嚢胞性線維症経膜コンダクタンスレギュレーター塩素チャンネルの三次構造は推定膜貫通ドメイン下方開口楕円構造を明らかにする

Author (11)： MIO Kazuhiro (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Ibaraki, JPN) ,  OGURA Toshihiko (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Ibaraki, JPN) ,  OGURA Toshihiko (JST-PRESTO, Saitama, JPN) ,  MIO Muneyo (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Ibaraki, JPN) ,  SHIMIZU Hiroyasu (Univ. Missouri, Missouri) ,  SHIMIZU Hiroyasu (Osaka Medical Coll., Osaka, JPN) ,  HWANG Tzyh-Chang (Univ. Missouri, Missouri) ,  SATO Chikara (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Ibaraki, JPN) ,  SOHMA Yoshiro (Univ. Missouri, Missouri) ,  SOHMA Yoshiro (Osaka Medical Coll., Osaka, JPN) ,  SOHMA Yoshiro (Keio Univ. School of Medicine, Tokyo, JPN)
Material： Journal of Biological Chemistry  (J Biol Chem)
Volume： 283  Issue： 44  Page： 30300-30310  Publication year： Oct. 31, 2008 
JST Material Number： E0038A  ISSN： 0021-9258  CODEN： JBCHA3  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： HEK293 cell ,  *ABC transporter ,  human ,  dimerization ,  Amino Acid Sequence ,  *Chloride Channels ,  *transmembrane protein ,  binding site ,  ATP binding protein ,  transmembrane domain ,  *CFTR ,  *Ion Transport ,  *transportation ,  *Biological Transport ,  *ion transport(in vivo)
Semi thesaurus term： *Cystic Fibrosis Transmembrane Conductance Regulator

JST classification (1)： Transport of cell membrane  (EF04020R)

Terms in the title (7)： ヒト ,  嚢胞性線維症 ,  塩素チャンネル ,  三次構造 ,  推定 ,  膜貫通ドメイン ,  楕円