Art

J-GLOBAL ID：200902299775416863   Reference number：07A1117510

Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Aripiprazole in Healthy Japanese Males

健常日本人男性でアリピプラゾールの薬物動力学の非線形混合効果モデル解析

Author (9)： KOUE Toshiko (Dep. of Clinical Res. and Dev., Otsuka Pharmaceutical Co., Ltd.) ,  KOUE Toshiko (Graduate School of Pharmaceutical Sciences, Univ. of Toyama) ,  KUBO Masanori (Dep. of Clinical Res. and Dev., Otsuka Pharmaceutical Co., Ltd.) ,  FUNAKI Tomoo (Dep. of Clinical Res. and Dev., Otsuka Pharmaceutical Co., Ltd.) ,  FUKUDA Tsuyoshi (Dep. of Clinical Evaluation of Medicines and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  AZUMA Junichi (Dep. of Clinical Evaluation of Medicines and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  TAKAAI Mari (Graduate School of Pharmaceutical Sciences, Univ. of Toyama) ,  KAYANO Yuichiro (Graduate School of Pharmaceutical Sciences, Univ. of Toyama) ,  HASHIMOTO Yukiya (Graduate School of Pharmaceutical Sciences, Univ. of Toyama)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 30  Issue： 11  Page： 2154-2158 (J-STAGE)  Publication year： 2007 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *analytical model ,...
Semi thesaurus term： NONMEM ,...

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JST classification (2)： Basic biopharmacy  (GY01021U) ,  Basic research of psychotropic drugs  (GW03100Y)

Substance index (2)： Aripiprazole ,  Itraconazol

Reference (21)：

• 1) Oshiro Y., Sato S., Kurahashi N., Tanaka T., Kikuchi T., Tottori K., Uwahodo Y., Nishi T., J. Med. Chem., 41, 658—667 (1998).
• 2) El-Sayeh H. G., Morganti C., Adams C. E., Br. J. Psychiatry, 189, 102—108 (2006).
• 3) Burris K. D., Molski T. F., Xu C., Ryan E., Tottori K., Kikuchi T., Yocca F. D., Molinoff P. B., J. Pharmacol. Exp. Ther., 302, 381—389 (2002).
• 4) Jordan S., Koprivica V., Chen R., Tottori K., Kikuchi T., Altar C. A., Eur. J. Pharmacol., 441, 137—140 (2002).
• 5) Package insert of Abilify^® (Aripiprazole, U.S.), April 2004 Revision, Otsuka America Pharmaceutical, Inc., Rockville, MD 20850, U.S.A. and Bristol-Myers Squibb Co., Princeton, NJ 08543, U.S.A.

Terms in the title (6)： 日本人 ,  男性 ,  アリピプラゾール ,  薬物動力学 ,  非線形混合効果モデル ,  解析