Art

J-GLOBAL ID：200902299930719193   Reference number：07A0124297

Dipalmitoylation of radicicol results in improved efficacy against tumor growth and angiogenesis in vivo

ラジシコールのジパルミトイル化は,in vivoにおいて腫瘍増殖と血管新生に対して改善効果を示す

Author (9)： OIKAWA Tsutomu (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  ONOZAWA Chizuko (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  KURANUKI Sachi (Kanagawa Univ. Human Serv., Kanagawa) ,  IGARASHI Yasuhiro (Toyama Prefectural Univ., Toyama) ,  SATO Mayumi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  ASHINO Hiromi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  SHIMAMURA Mariko (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  TOI Masakazu (Tokyo Metropolitan Komagome Hospital, Tokyo) ,  KURAKATA Shinichi (Sankyo Co., Tokyo, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 98  Issue： 2  Page： 219-225  Publication year： Feb. 2007 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *antitumor drug ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (2)： Radicicol ,  14,16-Dipalmitoylradicicol

Reference (56)：

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• HANAHAN, D. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996, 86, 353-364
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• KUWANO, M. The basic and clinical implications of ABC transporters, Y-box-binding protein-1 (YB-1) and angiogenesis-related factors in human malignancies. Cancer Sci. 2003, 94, 9-14
• SHIBUYA, M. Vascular endothelial growth factor receptor-2 : its unique signaling and specific ligand, VEGF-E. Cancer Sci. 2003, 94, 751-756

Terms in the title (4)： ラジシコール ,  腫瘍増殖 ,  血管新生 ,  改善効果