Rchr
J-GLOBAL ID：201001052499536517   Update date: Nov. 18, 2024

Kikawada Takahiro

キカワダ タカヒロ | Kikawada Takahiro
Affiliation and department：
National Institute of Agriculture and Food Research Organization Division of Biotechnology, Institute of Agrobiological Sciences

About National Institute of Agriculture and Food Research Organization Division of Biotechnology, Institute of Agrobiological Sciences


Job title： Group Leader
Other affiliations (1)：
Homepage URL  (1)： https://kaken.nii.ac.jp/search/?qm=60414900
Research field  (5)： Functional biochemistry ,  Molecular biology ,  Entomology ,  Biophysics ,  Conservation science (plants)
Research keywords  (24)： Dry preservation at room temperature ,  anhydrobiosis ,  comparative genomics ,  stress ,  adaptive evolution ,  genes ,  genome database ,  draft genomes ,  reparation ,  Diptera ,  function ,  proteins ,  Structures of nucleic acids ,  Drosophila melanogaster ,  LEA proteins ,  kinetics ,  Polypedilum vanderplanki ,  trehalose ,  desiccation tolerance ,  comprehensive analyses ,  insects ,  water absorption process ,  reparation of biomolecules ,  EST databases
Research theme for competitive and other funds  (24)：
  • 2023 - 2027 DryBrain: single cell-resolution molecular mechanisms ensuring tolerance of insect nervous system to complete desiccation
  • 2022 - 2026 Genome protection and repair mechanisms for the extreme desiccation tolerance, anhydrobiosis
  • 2022 - 2024 Elucidation of anhydrobiosis in Triops longicaudatus
  • 2020 - 2023 ExCells: biomimetic genomic platform for development of enhanced eukaryotic cell lines for biotechnological purposes
  • 2018 - 2023 Preservation of mammalian genetic resources and study for the developmental mechanism using freeze-dried cells
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Papers (91)：
  • Tsutomu Uchida, Tsubasa Hohana, Sumire Matsuo, Sakae Tsuda, Takahiro Kikawada. Effects of Trehalose and Antifreeze Glycoproteins on Long-Term Storage of Cryopreserved Trehalose-Transporter Expressing Cells and on Ice Recrystallization. Crystal Growth & Design. 2024
  • Clinton J. Belott, Oleg A. Gusev, Takahiro Kikawada, Michael A. Menze. Membraneless and membrane-bound organelles in an anhydrobiotic cell line are protected from desiccation-induced damage. Cell Stress and Chaperones. 2024. 29. 3. 425-436
  • Kosuke Mizutani, Yuki Yoshida, Eita Nakanishi, Yugo Miyata, Shoko Tokumoto, Hiroto Fuse, Oleg Gusev, Shingo Kikuta, Takahiro Kikawada. A sodium-dependent trehalose transporter contributes to anhydrobiosis in insect cell line, Pv11. Proceedings of the National Academy of Sciences. 2024. 121. 14. e2317254121
  • Richard Cornette, Hiroko P. Indo, Ken-ichi Iwata, Yuka Hagiwara-Komoda, Yuichi Nakahara, Oleg Gusev, Takahiro Kikawada, Takashi Okuda, Hideyuki J. Majima. Oxidative stress is an essential factor for the induction of anhydrobiosis in the desiccation-tolerant midge, Polypedilum vanderplanki (Diptera, Chironomidae). Mitochondrion. 2023
  • Fuse H, Kikawada T, Cornette R. Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance. Cytotechnology. 2023. 75. 491-503
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MISC (239)：
  • 黄川田隆洋, CORNETTE Richard. 干からびても死なない生物ネムリユスリカが持つ乾眠に必要な物質. 農研機構技報. 2022. 12. 18-21
  • 吉田祐貴, CORNETTE Richard, GUSEV Oleg, 黄川田隆洋. ネムリユスリカの極限環境適応へ寄与した染色体レベルのゲノムの偏り. 日本進化学会大会プログラム・講演要旨集(Web). 2022. 24th
  • 黄川田隆洋. Secret of not Dying from Drying out. 低温生物工学会セミナー及び年会講演要旨集. 2022. 67th
  • コルネット リシャー, SHAYKHUTDINOV Nurislam, グセフ オレグ, 黄川田隆洋, 奥田隆. アフリカの反乾燥地帯におけるユスリカ類の乾燥耐性の進化について. 日本応用動物昆虫学会大会講演要旨. 2021. 65th
  • 中西瑛太, CORNETTE Richard, 新井智彦, 吉田祐貴, 吉田祐貴, 徳本翔子, 宮田佑吾, GUSEV Oleg, GUSEV Oleg, 黄川田隆洋, et al. 強酸性湖に生息するサンユスリカ(Chironomus acerbiphilus Tokunaga)のゲノム解析. 日本応用動物昆虫学会大会講演要旨. 2021. 65th
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Patents (7)：
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Books (2)：
  • たけしの面白科学者図鑑 ヘンな生き物がいっぱい! (新潮文庫)
    新潮社 2017 ISBN:4101225354
  • Amazing world of the anhydrobiotic midge: Nemuriyusurika no fushigi na sekai : kono konchu wa naze ikikaeru koto ga dekiru noka
    Wedge press, Tokyo 2014 ISBN:4863101384
Lectures and oral presentations  (7)：
  • Effect of Ice Recrystallization Phenomenon on Long-Term Storage of Cryopreserved Cells
    (Summaries of JSSI and JSSE Joint Conference on Snow and Ice Research 2021)
  • トレハロースによるCHO-TRET1細胞の凍結保存実験 細胞内へのトレハロース輸送量の飽和量
    (低温生物工学会セミナー及び年会講演要旨集 2019)
  • Storage-period dependence on cryopreservation of CHO-K1 cells expressing trehalose transporter
    (Summaries of JSSI and JSSE Joint Conference on Snow and Ice Research 2018)
  • CHO細胞の凍結保存に最適な細胞内トレハロース濃度の推定
    (低温生物工学会セミナー及び年会講演要旨集 2017)
  • Studies on cryopreservation of cells with trehalose as a cryoprotectant
    (Summaries of JSSI and JSSE Joint Conference on Snow and Ice Research 2016)
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Education (2)：
  • 1992 - 1994 Iwate University Graduate School of Agriculture Agricultural Chemistry
  • 1988 - 1992 Iwate University Faculty of Agriculture Department of Agricultural Chemistry
Professional career (1)：
  • Ph.D (Tokyo Institute of Technology)
Work history (10)：
  • 2023/04 - 現在 The University of Tokyo Graduate School of Frontier Sciences Professor
  • 2023/04 - 現在 National Agriculture and Food Research Organization Biological Function Research Group, Division of Biomaterial Sciences, Institute of Agrobiological Sciences, NARO Gruop Leader
  • 2020/04 - 2023/03 National Agriculture and Food Research Organization Biological Function Research Group, Division of Biomaterial Sciences, Institute of Agrobiological Sciences, NARO Senior Research Scientist
  • 2015/04 - 2023/03 The University of Tokyo Graduate School of Frontier Sciences Associate Professor
  • 2019/10 - 2020/03 National Institute of Agriculture and Food Research Organization Molecular Biomimetics Research Unit, Division of Biotechnology, Institute of Agrobiological Sciences Senior Principal Researcher
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Committee career (2)：
  • 2014 - 2015 Japan Society for the Promotion of Science Review committee on Grants-in-Aid for Scientific Research
  • 2014 - 2015 日本学術振興会 科研費若手研究(B)・挑戦的萌芽研究 審査員
Awards (5)：
  • 2016/09 - Japan Society for the Promotion of Scince 2016 Best Reviewer Award on Grants-in-Aid for Scientific Research
  • 2012/06 - Japanese Society for Cryobiology and Cryotechnology Prize for young researcher in Cryobiology and Cryotechnology Molecular mechanisms underlying induction of anhydrobiosis in the sleeping chironomid
  • 2009/10 - Japanese Society of Extremophiles Prize for young researcher Molecular context of the extreme desiccation tolerance in the anhydrobiotic insect
  • 2007/12 - National Institute of Agrobiological Sciences NIAS prize in 2007 Molecular mechanisms underlying trehalose transport across cellular membrances
  • 2006/12 - Japan Transporter Research Association Best poster presentation award Roles of trehalose transporter TRET1 during induction of anhydrobiosis in the sleeping chironomid
Association Membership(s) (5)：
Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  The Molecular Biology of Japan ,  Japanese Society for Cryobiology and Cryotechnology ,  The Society for Extremopiles ,  トランスポーター研究会
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