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J-GLOBAL ID：201002201399900717   Reference number：10A1154466

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

ヒト人工多能性幹細胞を使った神経発生のモデルとRett症候群の治療

Author (9)： MARCHETTO Maria C.N. (The Salk Inst. for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  CARROMEU Cassiano (Univ. of California San Diego, School of Medicine, Dep. of Pediatrics, Rady Children’s Hospital San Diego, Dep. of ...) ,  ACAB Allan (Univ. of California San Diego, School of Medicine, Dep. of Pediatrics, Rady Children’s Hospital San Diego, Dep. of ...) ,  YU Diana (The Salk Inst. for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  YEO Gene W. (Univ. of California San Diego, School of Medicine, Dep. of Cellular & Molecular Medicine, Stem Cell Program, 9500 ...) ,  MU Yangling (The Salk Inst. for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  CHEN Gong (Pennylvania State Univ., Dep. of Biology. 201 Life Sci. Building, Univ. Park, PA 6802, USA) ,  GAGE Fred H. (The Salk Inst. for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  MUOTRI Alysson R. (Univ. of California San Diego, School of Medicine, Dep. of Pediatrics, Rady Children’s Hospital San Diego, Dep. of ...)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 143  Issue： 4  Page： 527-539  Publication year： Nov. 12, 2010 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Rett syndrome ,  *stem cell ,  *autism ,  human(primates) ,  fibroblast ,  product development ,  neuron ,  DNA binding protein ,  non-histone protein ,  woman ,  cell differentiation ,  genetic phenomenon ,  inactivation ,  differentiation(biology) ,  cell ,  synapse ,  ion pump(organism) ,  IGF1 ,  gentamicin ,  concentration(ratio) ,  calcium ,  nerve conduction ,  electric current ,  teratoma ,  nude mouse ,  *induced pluripotent stem cell
Semi thesaurus term： *Autism spectrum disorder ,  new drug development ,  MeCP2 protein ,  reprogramming ,  X Chromosome Inactivation ,  neurodifferentiation ,  neural precursor ,  glutamatergic neuron ,  Excitatory synapse ,  VGLUT1 ,  intracellular calcium concentration ,  postsynaptic current

JST classification (3)： Basic psychiatry  (GR01020I) ,  Cell physiology in general  (EF02010S) ,  Central nervous system  (EJ12030F)

Terms in the title (6)： ヒト ,  人工多能性幹細胞 ,  神経発生 ,  モデル ,  Rett症候群 ,  治療