Art

J-GLOBAL ID：201002208052384624   Reference number：10A0235622

Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumor markers

エピジェネティックサイレンシングおよび腫瘍低酸素症に誘発される癌におけるグリカン遺伝子の変異発現:新規腫瘍マーカーの進行中の探索における手掛かり

Author (8)： KANNAGI Reiji (Aichi Cancer Center, Aichi) ,  KANNAGI Reiji (Aichi Medical Univ., Aichi, JPN) ,  SAKUMA Keiichiro (Aichi Cancer Center, Aichi) ,  MIYAZAKI Keiko (Aichi Cancer Center, Aichi) ,  LIM Khe-Ti (Aichi Cancer Center, Aichi) ,  YUSA Akiko (Aichi Cancer Center, Aichi) ,  YIN Jun (Aichi Cancer Center, Aichi) ,  IZAWA Mineko (Aichi Cancer Center, Aichi)
Material： Cancer Science  (Cancer Sci)
Volume： 101  Issue： 3  Page： 586-593  Publication year： Mar. 2010 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 文献レビュー  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： エピジェネティックサイレンシング

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=10A0235622&from=J-GLOBAL&jstjournalNo=W1423A") }}

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Molecular genetics in general  (EC02010J)

Reference (59)：

• HAKOMORI, SI. Structure and function of glycosphingolipids and sphingolipids : recollections and future trends. Biochim Biophys Acta. 2008, 1780, 325-346
• HAKOMORI, S. Glycosphingolipid-dependent cross-talk between glycosynapses interfacing tumor cells with their host cells : essential basis to define tumor malignancy. FEBS Lett. 2002, 531, 88-92
• HAKOMORI, S. Glycosylation defining cancer malignancy : new wine in an old bottle. Proc Natl Acad Sci USA. 2002, 99, 10231-10233
• KANNAGI, R. Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants-Hakomori's concepts revisited. Biochim Biophys Acta. 2008, 1780, 525-531
• KANNAGI, R. Selectin-mediated metastasis of tumor cells : alteration of carbohydrate-mediated cell-cell interactions in cancers induced by epigenetic silencing of glycogenes. Glycobiology. 2007, 274-287

Terms in the title (10)： 腫瘍低酸素症 ,  誘発 ,  癌 ,  グリカン ,  遺伝子 ,  変異 ,  発現 ,  腫瘍マーカー ,  探索 ,  手掛かり